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How can nanotechnology help to combat COVID-19? Opportunities and urgent need.
Campos, Estefânia V R; Pereira, Anderson E S; de Oliveira, Jhones Luiz; Carvalho, Lucas Bragança; Guilger-Casagrande, Mariana; de Lima, Renata; Fraceto, Leonardo Fernandes.
  • Campos EVR; Human and Natural Sciences Center, Federal University of ABC. Av. dos Estados, 5001. Bl. A, T3 Lab. 503-3. Bangú, Santo André, SP, Brazil.
  • Pereira AES; São Paulo State University-UNESP, Institute of Science and Technology, Sorocaba, SP, Brazil.
  • de Oliveira JL; São Paulo State University-UNESP, Institute of Science and Technology, Sorocaba, SP, Brazil.
  • Carvalho LB; São Paulo State University-UNESP, Institute of Science and Technology, Sorocaba, SP, Brazil.
  • Guilger-Casagrande M; Universidade de Sorocaba, Rodovia Raposo Tavares km 92,5, Sorocaba, São Paulo, Brazil.
  • de Lima R; Universidade de Sorocaba, Rodovia Raposo Tavares km 92,5, Sorocaba, São Paulo, Brazil. renata.lima@prof.uniso.br.
  • Fraceto LF; São Paulo State University-UNESP, Institute of Science and Technology, Sorocaba, SP, Brazil. leonardo.fraceto@unesp.br.
J Nanobiotechnology ; 18(1): 125, 2020 Sep 05.
Article in English | MEDLINE | ID: covidwho-745681
ABSTRACT
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R0 values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Nanotechnology / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Nanobiotechnology Year: 2020 Document Type: Article Affiliation country: S12951-020-00685-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Nanotechnology / Pandemics / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Nanobiotechnology Year: 2020 Document Type: Article Affiliation country: S12951-020-00685-4