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Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia.
Radnis, Caitlin; Qiu, Sunny; Jhaveri, Miral; Da Silva, Ivan; Szewka, Aimee; Koffman, Lauren.
  • Radnis C; Department of Neurology, Rush University Medical Center, Chicago, IL 60612, USA. Electronic address: Caitlin_A_Radnis@rush.edu.
  • Qiu S; Department of Neurology, Rush University Medical Center, Chicago, IL 60612, USA.
  • Jhaveri M; Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
  • Da Silva I; Department of Neurology, Rush University Medical Center, Chicago, IL 60612, USA.
  • Szewka A; Department of Neurology, Rush University Medical Center, Chicago, IL 60612, USA.
  • Koffman L; Department of Neurology, Rush University Medical Center, Chicago, IL 60612, USA.
J Neurol Sci ; 418: 117119, 2020 11 15.
Article in English | MEDLINE | ID: covidwho-747743
ABSTRACT
The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. In this case series, we describe three cases of hypoxic brain injury seen on magnetic resonance imaging (MRI) in patients with hypoxemia secondary to COVID-19-related ARDS. The lack of severe observed hypoxemia in two of the cases suggests that unrecognized or asymptomatic hypoxemia may play a role in hypoxic brain injury related to COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Hypoxia / Nervous System Diseases Type of study: Case report / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: North America Language: English Journal: J Neurol Sci Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Hypoxia / Nervous System Diseases Type of study: Case report / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: North America Language: English Journal: J Neurol Sci Year: 2020 Document Type: Article