Molecular phylogeny and missense mutations at envelope proteins across coronaviruses.
Genomics
; 112(6): 4993-5004, 2020 11.
Article
in English
| MEDLINE | ID: covidwho-752712
ABSTRACT
Envelope (E) protein is one of the structural viroporins (76-109 amino acids long) present in the coronavirus. Sixteen sequentially different E-proteins were observed from a total of 4917 available complete SARS-CoV-2 genomes as on 18th June 2020 in the NCBI database. The missense mutations over the envelope protein across various coronaviruses of the ß-genus were analyzed to know the immediate parental origin of the envelope protein of SARS-CoV-2. The evolutionary origin is also endorsed by the phylogenetic analysis of the envelope proteins comparing sequence homology as well as amino acid conservations.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Coronavirus
/
Mutation, Missense
/
Coronavirus Envelope Proteins
Type of study:
Randomized controlled trials
Limits:
Animals
/
Humans
Language:
English
Journal:
Genomics
Journal subject:
Genetics
Year:
2020
Document Type:
Article
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