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Investigation on sleep and mental health of patients with Parkinson's disease during the Coronavirus disease 2019 pandemic.
Xia, Yun; Kou, Liang; Zhang, Guoxin; Han, Chao; Hu, Junjie; Wan, Fang; Yin, Sijia; Sun, Yadi; Wu, Jiawei; Li, Yunna; Zhang, Zhentao; Huang, Jinsha; Xiong, Nian; Wang, Tao.
  • Xia Y; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Kou L; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zhang G; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Han C; Department of Neurology, Anhui Provincial Hospital, The First Affiliated Hospital of Science and Technology of China, Hefei, China.
  • Hu J; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Wan F; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Yin S; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Sun Y; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Wu J; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Li Y; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zhang Z; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Huang J; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Xiong N; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Wang T; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: wangtaowh@hust.edu.cn.
Sleep Med ; 75: 428-433, 2020 11.
Article in English | MEDLINE | ID: covidwho-752846
ABSTRACT

BACKGROUND:

The coronavirus disease 2019 (COVID-19) pandemic is adversely affecting sleep quality and mental health, especially in individuals with chronic disease such as Parkinson's disease (PD).

METHODS:

We conducted a quantitative study, which included 119 Chinese PD patients who had been treated in an outpatient neurology clinic in Wuhan and 169 age- and sex-matched healthy controls. The questionnaire survey focused on the impact of the COVID-19 pandemic on sleep, mental status, symptoms, and daily life and medical treatment of PD patients.

RESULTS:

Compared to healthy controls, PD patients had significantly higher scores in both the Pittsburgh Sleep Quality Index (PSQI) (8.13 vs 5.36, p < 0.001) and the Hospital Anxiety and Depression Scale (HADS) -Depression (4.89 vs 3.82, p = 0.022), as well as a higher prevalence of sleep disturbances with PSQI > 5 points (68.9% vs 44.4%, p < 0.001). Sleep disturbance was identified in 68.9% of PD patients. A logistic regression analysis showed that sleep disturbance of PD patients was independently associated with exacerbation of PD symptoms (OR = 3.616, 95%CI= (1.479, 8.844), p = 0.005) and anxiety (OR = 1.379, 95%CI= (1.157, 1.642), p < 0.001). Compared to male PD patients, female ones had higher PSQI scores (9.28 ± 4.41 vs 7.03 ± 4.01, p = 0.009) and anxiety (32.8% vs 0.1%, p = 0.002) and depression prevalence (34.5% vs 11.5%, p = 0.003).

CONCLUSION:

The findings of the present study emphasize the importance of mental and sleep health interventions in PD patients during the COVID-19 pandemic. Additional attention should be paid to the difficulty encountered by PD patients in seeking medical treatment.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Anxiety / Parkinson Disease / Depression / Pandemics / COVID-19 / Sleep Initiation and Maintenance Disorders Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Sleep Med Journal subject: Neurology / Psychophysiology Year: 2020 Document Type: Article Affiliation country: J.sleep.2020.09.011

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Anxiety / Parkinson Disease / Depression / Pandemics / COVID-19 / Sleep Initiation and Maintenance Disorders Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Sleep Med Journal subject: Neurology / Psychophysiology Year: 2020 Document Type: Article Affiliation country: J.sleep.2020.09.011