Unusual arterial thrombotic events in Covid-19 patients.
Int J Cardiol
; 323: 281-284, 2021 01 15.
Article
in English
| MEDLINE | ID: covidwho-753509
ABSTRACT
INTRODUCTION:
COVID-19 infection is commonly complicated with pro-thrombotic state and endothelial dysfunction. While several studies reported a high incidence of venous thromboembolic events. The occurrence of arterial thromboses are yet rarely described and could be underestimated.OBJECTIVES:
To describe the clinical and biological characteristics of COVID-19 patients presenting with an associated arterial thromboembolic event. MATERIAL ANDMETHODS:
We performed a retrospective multicentric study in 3 centers between France and Italy. All patients with a confirmed SARS-CoV-2 infection and arterial thromboembolic events were included in the analysis.RESULTS:
From March 8th to April 25th 2020, we identified 20 patients (24 events) with arterial thromboembolic events over 209 admitted patients (9.6%) with severe COVID-19 infection. Arterial thrombotic events included acute coronary occlusions (n = 9), stroke (n = 6), limb ischemia (n = 3), splenic infarcts (n = 3), aortic thrombosis (n = 2) and occlusive mesenteric ischemia (n = 1). At the time of the event, 10/20 (50%) of patients received thromboprohylaxis, 2/20 (10%) were receiving treatment dose anticoagulation and 5/20 (25%) were receiving antiplatelet therapy.CONCLUSION:
Our observations suggest that serious arterial thrombotic events might occur in Covid-19 patients. However, the exact incidence of such events and the best way to prevent them yet remains to be investigated.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Splenic Infarction
/
Thrombosis
/
Stroke
/
Coronary Occlusion
/
Mesenteric Ischemia
/
COVID-19
/
Ischemia
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Journal:
Int J Cardiol
Year:
2021
Document Type:
Article
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