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Effect of the COVID-19 pandemic on acute stroke reperfusion therapy: data from the Lyon Stroke Center Network.
Plumereau, Cécile; Cho, Tae-Hee; Buisson, Marielle; Amaz, Camille; Cappucci, Matteo; Derex, Laurent; Ong, Elodie; Fontaine, Julia; Rascle, Lucie; Riva, Roberto; Schiavo, David; Benhamed, Axel; Douplat, Marion; Bony, Thomas; Tazarourte, Karim; Tuttle, Célia; Eker, Omer Faruk; Berthezène, Yves; Ovize, Michel; Nighoghossian, Norbert; Mechtouff, Laura.
  • Plumereau C; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Cho TH; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Buisson M; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Amaz C; CarMeN Laboratory, INSERM U1060, University Lyon 1, Lyon, France.
  • Cappucci M; Clinical Investigation Center, INSERM 1407, Hospices Civils de Lyon, Lyon, France.
  • Derex L; Clinical Investigation Center, INSERM 1407, Hospices Civils de Lyon, Lyon, France.
  • Ong E; Neuroradiology Department, Hospices Civils de Lyon, Lyon, France.
  • Fontaine J; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Rascle L; EA 7425 HESPER, Health Services and Performance Research, Claude Bernard Lyon 1 University, Lyon, France.
  • Riva R; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Schiavo D; CarMeN Laboratory, INSERM U1060, University Lyon 1, Lyon, France.
  • Benhamed A; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Douplat M; Department of Neurology, Stroke Center, Hospices Civils de Lyon, Lyon, France.
  • Bony T; Neuroradiology Department, Hospices Civils de Lyon, Lyon, France.
  • Tazarourte K; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Tuttle C; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Eker OF; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Berthezène Y; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Ovize M; Emergency Department, Hospices Civils de Lyon, Lyon, France.
  • Nighoghossian N; EA 7425 HESPER, Health Services and Performance Research, Claude Bernard Lyon 1 University, Lyon, France.
  • Mechtouff L; Neuroradiology Department, Hospices Civils de Lyon, Lyon, France.
J Neurol ; 268(7): 2314-2319, 2021 Jul.
Article in English | MEDLINE | ID: covidwho-754555
Semantic information from SemMedBD (by NLM)
1. Local disease PROCESS_OF Social Networks
Subject
Local disease
Predicate
PROCESS_OF
Object
Social Networks
2. Acute Cerebrovascular Accidents PROCESS_OF Patients
Subject
Acute Cerebrovascular Accidents
Predicate
PROCESS_OF
Object
Patients
3. Mechanical thrombectomy TREATS Patients
Subject
Mechanical thrombectomy
Predicate
TREATS
Object
Patients
4. IMPACT gene AUGMENTS Cerebrovascular accident
Subject
IMPACT gene
Predicate
AUGMENTS
Object
Cerebrovascular accident
5. Local disease PROCESS_OF Social Networks
Subject
Local disease
Predicate
PROCESS_OF
Object
Social Networks
6. Acute Cerebrovascular Accidents PROCESS_OF Patients
Subject
Acute Cerebrovascular Accidents
Predicate
PROCESS_OF
Object
Patients
7. Mechanical thrombectomy TREATS Patients
Subject
Mechanical thrombectomy
Predicate
TREATS
Object
Patients
8. IMPACT gene AUGMENTS Cerebrovascular accident
Subject
IMPACT gene
Predicate
AUGMENTS
Object
Cerebrovascular accident
ABSTRACT

BACKGROUND:

The coronavirus disease 2019 (COVID-19) pandemic would have particularly affected acute stroke care. However, its impact is clearly inherent to the local stroke network conditions. We aimed to assess the impact of COVID-19 pandemic on acute stroke care in the Lyon comprehensive stroke center during this period.

METHODS:

We conducted a prospective data collection of patients with acute ischemic stroke (AIS) treated with intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT) during the COVID-19 period (from 29/02/2020 to 10/05/2020) and a control period (from 29/02/2019 to 10/05/2019). The volume of reperfusion therapies and pre and intra-hospital delays were compared during both periods.

RESULTS:

A total of 208 patients were included. The volume of IVT significantly decreased during the COVID-period [55 (54.5%) vs 74 (69.2%); p = 0.03]. The volume of MT remains stable over the two periods [72 (71.3%) vs 65 (60.8%); p = 0.14], but the door-to-groin puncture time increased in patients transferred for MT (237 [187-339] vs 210 [163-260]; p < 0.01). The daily number of Emergency Medical Dispatch calls considerably increased (1502 [1133-2238] vs 1023 [960-1410]; p < 0.01).

CONCLUSIONS:

Our study showed a decrease in the volume of IVT, whereas the volume of MT remained stable although intra-hospital delays increased for transferred patients during the COVID-19 pandemic. These results contrast in part with the national surveys and suggest that the impact of the pandemic may depend on local stroke care networks.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombolytic Therapy / Brain Ischemia / Thrombectomy / Stroke / COVID-19 Type of study: Observational study / Risk factors Topics: Long Covid Limits: Humans Country/Region as subject: Europa Language: English Journal: J Neurol Year: 2021 Document Type: Article Affiliation country: S00415-020-10199-6

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombolytic Therapy / Brain Ischemia / Thrombectomy / Stroke / COVID-19 Type of study: Observational study / Risk factors Topics: Long Covid Limits: Humans Country/Region as subject: Europa Language: English Journal: J Neurol Year: 2021 Document Type: Article Affiliation country: S00415-020-10199-6