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Incidence and case fatality rate of COVID-19 in patients with inflammatory articular diseases.
Mena Vázquez, Natalia; Manrique-Arija, Sara; Cabezudo-García, Pablo; Godoy-Navarrete, Francisco Javier; Cabezas-Lucena, Alba María; Morales-Águila, M; Redondo-Rodríguez, Roció; Sobrino, Beatriz; Ureña-Garnica, Inmaculada; Ordoñez-Cañizares, M C; Díaz Cordovés-Rego, Gisela; Fernández-Nebro, Antonio.
  • Mena Vázquez N; UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Manrique-Arija S; Unidad de Gestión Clínica (UCG) de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Cabezudo-García P; Instituto de Investigación Biomédica de Málaga (IBIMA), Servicio de Neurología, UGC de Neurociencias, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Godoy-Navarrete FJ; Unidad de Gestión Clínica (UCG) de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Cabezas-Lucena AM; Unidad de Gestión Clínica (UCG) de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Morales-Águila M; Unidad de Gestión Clínica (UCG) de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Redondo-Rodríguez R; Unidad de Gestión Clínica (UCG) de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Sobrino B; Unidad de Gestión Clínica (UCG) de Enfermedades Infecciosas, Instituto de Investigación Biomédica de Málaga (IBIMA),, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Ureña-Garnica I; UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Ordoñez-Cañizares MC; UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Díaz Cordovés-Rego G; UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
  • Fernández-Nebro A; UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.
Int J Clin Pract ; 75(4): e13707, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-760138
Semantic information from SemMedBD (by NLM)
1. inflammatory joint disease PROCESS_OF Patients
Subject
inflammatory joint disease
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PROCESS_OF
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Patients
2. COVID-19 OCCURS_IN Patients
Subject
COVID-19
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OCCURS_IN
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Patients
3. risk factors PROCESS_OF Patients
Subject
risk factors
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PROCESS_OF
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Patients
4. Rheumatoid Arthritis PROCESS_OF Patients
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Rheumatoid Arthritis
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PROCESS_OF
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Patients
5. COVID-19 PROCESS_OF Patients
Subject
COVID-19
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PROCESS_OF
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Patients
6. COVID-19 COEXISTS_WITH Arthriti
Subject
COVID-19
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COEXISTS_WITH
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Arthriti
7. Senility PROCESS_OF Patients
Subject
Senility
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PROCESS_OF
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Patients
8. inflammatory joint disease PROCESS_OF Patients
Subject
inflammatory joint disease
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Patients
9. COVID-19 OCCURS_IN Patients
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COVID-19
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10. risk factors PROCESS_OF Patients
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risk factors
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Patients
11. Rheumatoid Arthritis PROCESS_OF Patients
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Rheumatoid Arthritis
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Patients
12. COVID-19 PROCESS_OF Patients
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13. COVID-19 COEXISTS_WITH Arthritis, Psoriatic
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Arthritis, Psoriatic
14. Senility PROCESS_OF Patients
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ABSTRACT

OBJECTIVE:

To describe the incidence and fatality of coronavirus disease 2019 (COVID-19) and identify risk factors to fatality in patients with inflammatory articular diseases (IAD).

METHODS:

This is a cross-sectional observational study of IAD patients and COVID-19 with controls matched for age, sex, and RT-PCR. A control group was used to compare the cumulative incidence (CI) and case fatality rate (CFR). The main outcomes of the study were CI and CFR. Other variables included comorbidities, treatments, and characteristics of the COVID-19. Multiple logistic regression analysis was performed to investigate risk factors for fatality in patients with IAD.

RESULTS:

Of the 1537 patients who fulfilled the inclusion criteria, 23/1537 (1.49%) had IAD 13 (0.8%) had rheumatoid arthritis (RA), 5 psoriatic arthritis (PsA) (0.3%) and 5 axial spondyloarthritis (0.3%). There were no significant differences in CI of COVID-19 and CFR in patients with IAD compared with COVID-19 patients without IAD. In RT-PCR positive patients, the CI of COVID-19 in PsA and AS was higher. Of the 23 IAD patients, 2 RA patients (8.6%) died. The patients did no show characteristics of the COVID-19 disease different from the population. In multivariate analysis, the factor associated with fatality in patients with IAD was older age (OR [95% CI], 1.1 [1.0-1.2]).

CONCLUSION:

COVID-19 CI, fatality rate and other features do not seem to be increased in IAD patients. Older age was associated with fatality in patients with IAD.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Joint Diseases Type of study: Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Randomized controlled trials / Risk factors Limits: Aged / Humans Language: English Journal: Int J Clin Pract Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Ijcp.13707

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Joint Diseases Type of study: Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Randomized controlled trials / Risk factors Limits: Aged / Humans Language: English Journal: Int J Clin Pract Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Ijcp.13707