Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 Stability in Multiple Water Matrices
J Korean Med Sci
; 35(36):e330, 2020.
Article
in English
| PubMed | ID: covidwho-760855
ABSTRACT
The advent of the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates a thorough study of the stability and transmissibility in the environment. We characterized the stability of SARS-CoV-2 in three water matrices fresh, tap, and seawater. The minimum infective dose of SARS-CoV-2 in Vero cells was confirmed to be 10³ PFU/mL. The stability of SARS-CoV-2 varied according to the water matrix infective SARS-CoV-2 was undetectable after treatment with fresh water and seawater, but remained detectable for 2 days in tap water, when starting with an initial concentration of 10⁴ PFU/mL. When the starting concentration was increased to 10⁵ PFU/mL, a similar trend was observed. In addition, viral RNA persisted longer than infectious virus in all water matrices. This study was conducted in stagnant water containing a significantly high titer of virus, thus, human-to-human transmission of SARS-CoV-2 through the actual aquatic environment is expected to be rare.
Full text:
Available
Collection:
Databases of international organizations
Database:
PubMed
Language:
English
Journal:
J Korean Med Sci
Year:
2020
Document Type:
Article
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