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Polyphenols vs. Coronaviruses: How Far Has Research Moved Forward?
Piccolella, Simona; Crescente, Giuseppina; Faramarzi, Shadab; Formato, Marialuisa; Pecoraro, Maria Tommasina; Pacifico, Severina.
  • Piccolella S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
  • Crescente G; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
  • Faramarzi S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
  • Formato M; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
  • Pecoraro MT; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
  • Pacifico S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Via Vivaldi 43, 81100 Caserta, Italy.
Molecules ; 25(18)2020 Sep 08.
Article in English | MEDLINE | ID: covidwho-760942
ABSTRACT
The epidemic, caused by SARS-CoV-2 at the beginning of 2020, led us to a serious change in our lifestyle that for about three months has confined us to our homes, far from our laboratory routine. In this period, the belief that the work of a researcher should never stop has been the driving force in writing the present paper. It aims at reviewing the recent scientific knowledge about in vitro experimental data that focused on the antiviral role of phenols and polyphenols against different species of coronaviruses (CoVs), pointing up the viral targets potentially involved. In the current literature scenario, the papain-like and the 3-chymotrypsin-like proteases seem to be the most deeply investigated and a number of isolated natural (poly)phenols has been screened for their efficacy.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus / Biomedical Research / Polyphenols Limits: Animals / Humans Language: English Journal subject: Biology Year: 2020 Document Type: Article Affiliation country: Molecules25184103

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus / Biomedical Research / Polyphenols Limits: Animals / Humans Language: English Journal subject: Biology Year: 2020 Document Type: Article Affiliation country: Molecules25184103