Negative nasopharyngeal swabs in COVID-19 pneumonia: the experience of an Italian Emergengy Department (Piacenza) during the first month of the Italian epidemic.
Acta Biomed
; 91(3): e2020024, 2020 09 07.
Article
in English
| MEDLINE | ID: covidwho-761235
ABSTRACT
Coronavirus disease (COVID-19) is a systemic disease which can cause multiple organ failure and death primarly due to vascular endothelium injury. Severe acute respiratory distress syndrome (ARDS) is the main cause of death its management and treatment should be tailored to the individual COVID-19 patient's phenotype. Early diagnosis of COVID-19 is paramount for disease treatment and infection control. Naso-pharyngeal (NP) swab is commonly used as screening and diagnostic tool for COVID-19, but in some cases it can be resulted negative even in presence of clinical and epidemiological criteria, and typical radiological and laboratory findings of COVID-19, as we have observed. Here we report our experience in the first month of the Italian epidemic. We strongly recommend clinicians to maintain a high index of suspicion for COVID-19, regardless of the persistence negativity of NP swabs, and not to delay the initiation of therapy in presence of typical clinical, radiological and laboratory findings of COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Nasopharynx
/
Coronavirus Infections
/
Emergency Service, Hospital
/
Pandemics
/
Betacoronavirus
/
Antibodies, Viral
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Acta Biomed
Journal subject:
Medicine
Year:
2020
Document Type:
Article
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