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Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China.
Dai, Meng-Yuan; Chen, Zhen; Leng, Yan; Wu, Meng; Liu, Yu; Zhou, Fuxiang; Ming, Chen; Shao, Ningyi; Liu, Miao; Cai, Hongbing.
  • Dai MY; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Chen Z; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.
  • Leng Y; Hubei Cancer Clinical Study Center, Wuhan, China.
  • Wu M; Department of Emergency, The Central Hospital of Wuhan affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
  • Liu Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Zhou F; Department of Ultrasound, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Ming C; Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Shao N; Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Liu M; Department of Genetics and Genomic Sciences, Icahn School of Medicine, Mount Sinai, NY, USA.
  • Cai H; Faculty of Health Sciences, University of Macau, Macau, China.
Cancer Control ; 27(1): 1073274820960467, 2020.
Article in English | MEDLINE | ID: covidwho-772066
ABSTRACT
Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus / Lung Neoplasms Type of study: Observational study / Prognostic study Topics: Long Covid Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Cancer Control Journal subject: Neoplasms Year: 2020 Document Type: Article Affiliation country: 1073274820960467

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Pandemics / Betacoronavirus / Lung Neoplasms Type of study: Observational study / Prognostic study Topics: Long Covid Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Cancer Control Journal subject: Neoplasms Year: 2020 Document Type: Article Affiliation country: 1073274820960467