Cytokine storm and use of anakinra in a patient with COVID-19.
BMJ Case Rep
; 13(9)2020 Sep 15.
Article
in English
| MEDLINE | ID: covidwho-772245
ABSTRACT
We present a case of a 50-year-old man with COVID-19 infection and acute respiratory distress syndrome as a result of a cytokine storm and use of anakinra, an interleukin 1-receptor antagonist that is normally used in the treatment of autoinflammatory disorders in adult patients. We saw a reduction in oxygen requirement and improvements in inflammatory markers and ferritin. Although we cannot determine its clinical efficacy from one case study, it may have a positive effect on the proinflammatory state that is associated with cytokine storm in COVID-19 infection.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Cytokines
/
Coronavirus Infections
/
Interleukin 1 Receptor Antagonist Protein
Type of study:
Case report
/
Prognostic study
Limits:
Humans
/
Male
/
Middle aged
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Bcr-2020-237525
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