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CRISPR/Cas13: A potential therapeutic option of COVID-19.
Lotfi, Melika; Rezaei, Nima.
  • Lotfi M; School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran; USERN Office, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Rezaei N; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: rezaei_nima@tums.ac.ir.
Biomed Pharmacother ; 131: 110738, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-773856
ABSTRACT
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high mortality and morbidity rates all around the world. Although scientists are trying to discover novel therapies and develop and evaluate various previous treatments, at the time of writing this paper, there was no definite therapy and vaccine for COVID-19. So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / RNA, Viral / Genetic Therapy / Coronavirus Infections / CRISPR-Cas Systems / Gene Editing / Betacoronavirus Type of study: Experimental Studies Topics: Vaccines Limits: Humans Language: English Journal: Biomed Pharmacother Year: 2020 Document Type: Article Affiliation country: J.biopha.2020.110738

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / RNA, Viral / Genetic Therapy / Coronavirus Infections / CRISPR-Cas Systems / Gene Editing / Betacoronavirus Type of study: Experimental Studies Topics: Vaccines Limits: Humans Language: English Journal: Biomed Pharmacother Year: 2020 Document Type: Article Affiliation country: J.biopha.2020.110738