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Atypical presentation of COVID-19 in hospitalised older adults.
Gan, Jasmine Ming; Kho, Jason; Akhunbay-Fudge, Michelle; Choo, Hwei Ming; Wright, Melanie; Batt, Farzana; Mandal, Amit K J; Chauhan, Rahul; Missouris, Constantinos G.
  • Gan JM; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Kho J; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Akhunbay-Fudge M; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Choo HM; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Wright M; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Batt F; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Mandal AKJ; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK. amit.mandal@nhs.net.
  • Chauhan R; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
  • Missouris CG; Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
Ir J Med Sci ; 190(2): 469-474, 2021 May.
Article in English | MEDLINE | ID: covidwho-778059
ABSTRACT

BACKGROUND:

It is increasingly recognised that older patients may not present with typical symptoms of COVID-19.

AIMS:

This study aims to evaluate the incidence, characteristics and clinical outcome of older adults with atypical presentations of COVID-19.

METHODS:

A retrospective analysis of adults ≥ 65 years with confirmed COVID-19 admitted to our institution between 1 March and 24 April 2020 was performed. Patients were categorised into typical or atypical groups based on primary presenting complaint in the community.

RESULTS:

One hundred twenty-two patients (mean age 81 ± 8 years; 62 male) were included. Seventy-three (60%) were categorised into the typical group and 49 (40%) into the atypical group. In the atypical group, common presenting complaints were fall in 18 (36%), reduced mobility or generalised weakness in 18 (36%) and delirium in 11 (22%). Further assessment by paramedics and on admission found 32 (65%) to have typical features of COVID-19, fever being the most common, and 22 (44%) were hypoxic. This subset had worse outcomes than those in the typical group with a mortality rate of 50% versus 38%, respectively, although this was not statistically significant (P = 0.27). No significant difference in mortality or length of hospital stay between the groups was demonstrated.

CONCLUSION:

Older patients with atypical presentation of COVID-19 in the community are equally susceptible to poor outcomes. Early detection may improve outcomes and limit community transmission. Primary care practitioners should be vigilant and consider prompt onward referral.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male Language: English Journal: Ir J Med Sci Year: 2021 Document Type: Article Affiliation country: S11845-020-02372-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male Language: English Journal: Ir J Med Sci Year: 2021 Document Type: Article Affiliation country: S11845-020-02372-7