COVID-19 infection in patients on anti-complement therapy: The Leeds National Paroxysmal Nocturnal Haemoglobinuria service experience.

Pike, Alexandra; Muus, Petra; Munir, Tahla; Mitchell, Lindsay; Arnold, Louise; Riley, Kathryn; Houghton, Nicola; Forrest, Briony; Gachev, Jeanifer; Hillmen, Peter; Griffin, Morag

Pike, Alexandra; Muus, Petra; Munir, Tahla; Mitchell, Lindsay; Arnold, Louise; Riley, Kathryn; Houghton, Nicola; Forrest, Briony; Gachev, Jeanifer; Hillmen, Peter; Griffin, Morag.

Pike A; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Muus P; Section of Experimental Haematology, Leeds Institute of Medical Research at St. James's, School of Medicine, University of Leeds, Leeds, UK.
Munir T; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Mitchell L; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Arnold L; Department of Haematology, University Hospital Monklands, Airdrie, Lanarkshire, UK.
Riley K; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Houghton N; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Forrest B; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Gachev J; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Hillmen P; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Griffin M; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Br J Haematol ; 191(1): e1-e4, 2020 10.

Article in English | MEDLINE | ID: covidwho-780768

Subject(s)

Antibodies, Monoclonal, Humanized/adverse effects; COVID-19/complications; Complement C5/antagonists & inhibitors; Complement Inactivating Agents/adverse effects; Hemoglobinuria, Paroxysmal/complications; SARS-CoV-2; Adult; Aged; Anemia, Aplastic/complications; Antibodies, Monoclonal, Humanized/therapeutic use; COVID-19/blood; Comorbidity; Complement Inactivating Agents/therapeutic use; Disease Susceptibility; Fatal Outcome; Female; Hemoglobinuria, Paroxysmal/drug therapy; Hemolysis; Hospitalization; Humans; Immunocompromised Host; Male; Middle Aged; Pneumonia, Bacterial/etiology; Respiratory Distress Syndrome/etiology; Superinfection

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Complement C5 / Complement Inactivating Agents / Antibodies, Monoclonal, Humanized / SARS-CoV-2 / COVID-19 / Hemoglobinuria, Paroxysmal Type of study: Case report / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Br J Haematol Year: 2020 Document Type: Article Affiliation country: Bjh.17097

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