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Neutrophils and Contact Activation of Coagulation as Potential Drivers of COVID-19.
Busch, Matthias H; Timmermans, Sjoerd A M E G; Nagy, Magdolna; Visser, Mayken; Huckriede, Joram; Aendekerk, Joop P; de Vries, Femke; Potjewijd, Judith; Jallah, Borefore; Ysermans, Renée; Oude Lashof, Astrid M L; Breedveld, Paul H; van de Poll, Marcel C G; van de Horst, Iwan C C; van Bussel, Bas C T; Theunissen, Ruud O M F I H; Spronk, Henri M H; Damoiseaux, Jan G M C; Ten Cate, Hugo; Nicolaes, Gerry A F; Reutelingsperger, Chris P; van Paassen, Pieter.
  • Busch MH; Department of Nephrology and Clinical Immunology (M.H.B., S.A.M.E.G.T., J.P., B.J., R.Y., P.v.P.), Maastricht University Medical Center, The Netherlands.
  • Timmermans SAMEG; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Nagy M; Department of Nephrology and Clinical Immunology (M.H.B., S.A.M.E.G.T., J.P., B.J., R.Y., P.v.P.), Maastricht University Medical Center, The Netherlands.
  • Visser M; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Huckriede J; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Aendekerk JP; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • de Vries F; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Potjewijd J; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Jallah B; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Ysermans R; Department of Nephrology and Clinical Immunology (M.H.B., S.A.M.E.G.T., J.P., B.J., R.Y., P.v.P.), Maastricht University Medical Center, The Netherlands.
  • Oude Lashof AML; Department of Nephrology and Clinical Immunology (M.H.B., S.A.M.E.G.T., J.P., B.J., R.Y., P.v.P.), Maastricht University Medical Center, The Netherlands.
  • Breedveld PH; Department of Nephrology and Clinical Immunology (M.H.B., S.A.M.E.G.T., J.P., B.J., R.Y., P.v.P.), Maastricht University Medical Center, The Netherlands.
  • van de Poll MCG; Department of Medical Microbiology (A.M.L.O.L.), Maastricht University Medical Center, The Netherlands.
  • van de Horst ICC; Department of Surgery (P.H.B.), Maastricht University Medical Center, The Netherlands.
  • van Bussel BCT; Department of Intensive Care Medicine (M.C.G.v.d.P., I.C.C.v.d.H., B.C.T.v.B.), Maastricht University Medical Center, The Netherlands.
  • Theunissen ROMFIH; Department of Intensive Care Medicine (M.C.G.v.d.P., I.C.C.v.d.H., B.C.T.v.B.), Maastricht University Medical Center, The Netherlands.
  • Spronk HMH; Department of Intensive Care Medicine (M.C.G.v.d.P., I.C.C.v.d.H., B.C.T.v.B.), Maastricht University Medical Center, The Netherlands.
  • Damoiseaux JGMC; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Ten Cate H; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
  • Nicolaes GAF; Central Diagnostic Laboratory (J.G.M.C.D.), Maastricht University Medical Center, The Netherlands.
  • Reutelingsperger CP; Thrombosis Expertise Center (H.t.C.), Maastricht University Medical Center, The Netherlands.
  • van Paassen P; Department of Biochemistry, Cardiovascular Research Institute, Maastricht, The Netherlands (M.H.B., S.A.M.E.G.T., M.N., M.V., J.H., J.P.A., F.d.V., R.O.M.F.I.H.T., H.M.H.S., H.t.C., G.A.F.N., C.P.R., P.v.P.).
Circulation ; 142(18): 1787-1790, 2020 11 03.
Article in English | MEDLINE | ID: covidwho-781268

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Thrombosis / Blood Coagulation / Coronavirus Infections / Complement Activation / Thrombophilia / Extracellular Traps / Betacoronavirus / Neutrophils Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Circulation Year: 2020 Document Type: Article Affiliation country: Circulationaha.120.050656

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Thrombosis / Blood Coagulation / Coronavirus Infections / Complement Activation / Thrombophilia / Extracellular Traps / Betacoronavirus / Neutrophils Limits: Aged / Female / Humans / Male / Middle aged Language: English Journal: Circulation Year: 2020 Document Type: Article Affiliation country: Circulationaha.120.050656