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Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) among Patients at a Movement Disorders Center.
de Marcaida, Joy Antonelle; Lahrmann, Jeffrey; Machado, Duarte; Bluth, Lawrence; Dagostine, Michelle; Moro-de Casillas, Maria; Bortan, Elena; Kanchana, Sulada; Alberts, Mark.
  • de Marcaida JA; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Lahrmann J; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Machado D; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Bluth L; Hartford Neurology LLC, Hartford, CT 06066, USA.
  • Dagostine M; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Moro-de Casillas M; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Bortan E; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Kanchana S; Chase Family Movement Disorders Center, Hartford HealthCare, Hartford, CT 06066, USA.
  • Alberts M; Ayer Neuroscience Institute, Hartford HealthCare, Hartford, CT 06066, USA.
Geriatrics (Basel) ; 5(3)2020 Sep 18.
Article in English | MEDLINE | ID: covidwho-789344
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Movement Disorders PROCESS_OF Patients
Subject
Movement Disorders
Predicate
PROCESS_OF
Object
Patients
3. COVID-19 PROCESS_OF General Population
Subject
COVID-19
Predicate
PROCESS_OF
Object
General Population
4. Abnormal mental state PROCESS_OF Patients
Subject
Abnormal mental state
Predicate
PROCESS_OF
Object
Patients
5. Generalized muscle weakness PROCESS_OF Patients
Subject
Generalized muscle weakness
Predicate
PROCESS_OF
Object
Patients
6. Worse PROCESS_OF Patients
Subject
Worse
Predicate
PROCESS_OF
Object
Patients
7. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
8. Movement Disorders PROCESS_OF Patients
Subject
Movement Disorders
Predicate
PROCESS_OF
Object
Patients
9. COVID-19 PROCESS_OF General Population
Subject
COVID-19
Predicate
PROCESS_OF
Object
General Population
10. Abnormal mental state PROCESS_OF Patients
Subject
Abnormal mental state
Predicate
PROCESS_OF
Object
Patients
11. Generalized muscle weakness PROCESS_OF Patients
Subject
Generalized muscle weakness
Predicate
PROCESS_OF
Object
Patients
12. Worse PROCESS_OF Patients
Subject
Worse
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
It is not established whether SARS-CoV-2 (COVID-19) patients with movement disorders, are at greater risk for more serious outcomes than the larger COVID-19 population beyond the susceptibility associated with greater age. We reviewed electronic health records and conducted telephone interviews to collect the demographics and clinical outcomes of patients seen at our Movement Disorders Center who tested positive for COVID-19 from 8 March 2020 through 6 June 2020. Thirty-six patients were identified, 23 men and 13 women, median age of 74.5 years. They primarily carried diagnoses of idiopathic Parkinson disease (n = 22; 61%) and atypical parkinsonism (n = 7; 19%) with the balance having other diagnoses. Twenty-seven patients (75%) exhibited alteration in mental status and fifteen (42%) had abnormalities of movement as common manifestations of COVID-19; in 61% and 31%, respectively, these were the presenting symptoms of the disease. Sixty-seven percent of patients in our cohort required hospitalization, and the mortality rate was 36%. These data demonstrate that in patients with movement disorders, the likelihood of hospitalization and death after contracting COVID-19 was greater than in the general population. Patients with movement disorders frequently presented with altered mental status, generalized weakness, or worsening mobility but not anosmia.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Year: 2020 Document Type: Article Affiliation country: Geriatrics5030054

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Year: 2020 Document Type: Article Affiliation country: Geriatrics5030054