Sexual Dimorphism of Coronavirus 19 Morbidity and Lethality.
Trends Endocrinol Metab
; 31(12): 918-927, 2020 12.
Article
in English
| MEDLINE | ID: covidwho-791591
ABSTRACT
The recent coronavirus disease 2019 (COVID-19) pandemic showed a different severity in the disease between males and females. Men have been becoming severely ill at a higher rate than women. These data along with an age-dependent disease susceptibility and mortality in the elderly suggest that sex hormones are the main factors in determining the clinical course of the infection. The differences in aging males versus females and the role of sex hormones in key phenotypes of COVID-19 infection are described in this review. Recommendations based on a dimorphic approach for males and females suggest a sex-specific management the disease.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Sex Factors
/
Estrogens
/
COVID-19
/
Androgens
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Trends Endocrinol Metab
Journal subject:
Endocrinology
/
Metabolism
Year:
2020
Document Type:
Article
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