Omega-3 fatty acids in the psychological and physiological resilience against COVID-19.

Chang, Jane Pei-Chen; Pariante, Carmine M; Su, Kuan-Pin

Chang, Jane Pei-Chen; Pariante, Carmine M; Su, Kuan-Pin.

Chang JP; Mind-Body Interface Laboratory (MBI-Lab) and Department of Psychiatry, China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Pariante CM; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Su KP; Mind-Body Interface Laboratory (MBI-Lab) and Department of Psychiatry, China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; An-Nan Hospital, China Medical University, Tainan, Taiwan. Electronic address: cobolsu@gmail.com.

Prostaglandins Leukot Essent Fatty Acids ; 161: 102177, 2020 10.

Article in English | MEDLINE | ID: covidwho-796199

ABSTRACT

ABSTRACT

As the infected cases of COVID-19 reach more than 20 million with more than 778,000 deaths globally, an increase in psychiatric disorders including anxiety and depression has been reported. Scientists globally have been searching for novel therapies and vaccines to fight against COVID-19. Improving innate immunity has been suggested to block progression of COVID-19 at early stages, while omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been shown to have immunomodulation effects. Moreover, n-3 PUFAs have also been shown to improve mood disorders, thus, future research is warranted to test if n-3 PUFAs may have the potential to improve our immunity to counteract both physical and mental impact of COVID-19.

Subject(s)

Anxiety/prevention & control; Coronavirus Infections/prevention & control; Depression/prevention & control; Dietary Supplements; Fatty Acids, Omega-3/administration & dosage; Immunologic Factors/administration & dosage; Pandemics/prevention & control; Pneumonia, Viral/prevention & control; Anxiety/immunology; Anxiety/metabolism; Anxiety/virology; Betacoronavirus/immunology; Betacoronavirus/pathogenicity; COVID-19; Coronavirus Infections/immunology; Coronavirus Infections/metabolism; Coronavirus Infections/virology; Cytokines/biosynthesis; Cytokines/immunology; Dendritic Cells/drug effects; Dendritic Cells/immunology; Dendritic Cells/virology; Depression/immunology; Depression/metabolism; Depression/virology; Epithelial Cells/drug effects; Epithelial Cells/immunology; Epithelial Cells/virology; Fatty Acids, Omega-3/immunology; Fatty Acids, Omega-3/metabolism; Host-Pathogen Interactions/drug effects; Host-Pathogen Interactions/immunology; Humans; Immunity, Innate/drug effects; Immunologic Factors/immunology; Immunologic Factors/metabolism; Lymphocytes/drug effects; Lymphocytes/immunology; Lymphocytes/virology; Macrophages/drug effects; Macrophages/immunology; Macrophages/virology; Pneumonia, Viral/immunology; Pneumonia, Viral/metabolism; Pneumonia, Viral/virology; SARS-CoV-2

Keywords

Covid-19; Immunomodulation; Omega-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Anxiety / Pneumonia, Viral / Fatty Acids, Omega-3 / Coronavirus Infections / Dietary Supplements / Depression / Pandemics / Immunologic Factors Type of study: Observational study Topics: Traditional medicine / Vaccines Language: English Journal: Prostaglandins Leukot Essent Fatty Acids Journal subject: Endocrinology Year: 2020 Document Type: Article Affiliation country: J.plefa.2020.102177

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