Your browser doesn't support javascript.
Dynamics of viral load and anti-SARS-CoV-2 antibodies in patients with positive RT-PCR results after recovery from COVID-19.
Song, Kyoung-Ho; Kim, Dong-Min; Lee, Hyunju; Ham, Sin Young; Oh, Sang-Min; Jeong, Hyeonju; Jung, Jongtak; Kang, Chang Kyung; Park, Ji Young; Kang, Yu Min; Kim, Ji-Yeon; Park, Jeong Su; Park, Kyoung Un; Kim, Eu Suk; Kim, Hong Bin.
  • Song KH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kim DM; Department of Internal Medicine, Chosun University Hospital, Gwangju, Korea.
  • Lee H; Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Ham SY; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Oh SM; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Jeong H; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Jung J; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kang CK; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
  • Park JY; Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kang YM; Division of Infectious Diseases, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.
  • Kim JY; Department of Infectious Diseases, Seongnam Citizens Medical Center, Seongnam, Korea.
  • Park JS; Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Park KU; Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kim ES; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • Kim HB; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Korean J Intern Med ; 36(1): 11-14, 2021 01.
Article in English | MEDLINE | ID: covidwho-798105
ABSTRACT
Recently, the number of patients with coronavirus disease 2019 (COVID-19) who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), via the reverse transcription polymerase chain reaction (RT-PCR) test, after recovery has increased; this has caused a dilemma regarding the medical measures and policies. We evaluated the dynamics of viral load and anti-SARS-CoV-2 antibodies in four patients with positive RT-PCR results after recovery. In all patients, the highest levels of immunoglobulin G (IgG) and IgM antibodies were reached after about a month of the onset of the initial symptoms. Then, the IgG titers plateaued, and the IgM titers decreased, regardless of RT-PCR results. The IgG and IgM levels did not increase after the post-negative positive RT-PCR results in any of the patients. Our results reinforced that the post-negative positive RT-PCR results may be due to the detection of RNA particles rather than reinfection in individuals who have recovered from COVID-19.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Viral / Viral Load / Reverse Transcriptase Polymerase Chain Reaction / COVID-19 Nucleic Acid Testing / COVID-19 Serological Testing / SARS-CoV-2 / COVID-19 / Antibodies, Viral Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Infant / Male Language: English Journal: Korean J Intern Med Journal subject: Internal Medicine Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Viral / Viral Load / Reverse Transcriptase Polymerase Chain Reaction / COVID-19 Nucleic Acid Testing / COVID-19 Serological Testing / SARS-CoV-2 / COVID-19 / Antibodies, Viral Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Infant / Male Language: English Journal: Korean J Intern Med Journal subject: Internal Medicine Year: 2021 Document Type: Article