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COVID-19 Infection: Concise Review Based on the Immunological Perspective.
Lotfinejad, Parisa; Asadzadeh, Zahra; Najjary, Shiva; Somi, Mohammad Hossein; Hajiasgharzadeh, Khalil; Mokhtarzadeh, Ahad; Derakhshani, Afshin; Roshani, Elmira; Baradaran, Behzad.
  • Lotfinejad P; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Asadzadeh Z; Department of Immunology, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Najjary S; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Somi MH; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Hajiasgharzadeh K; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Mokhtarzadeh A; Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Derakhshani A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Roshani E; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Immunol Invest ; 51(2): 246-265, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-799529
ABSTRACT
The outbreak of coronavirus disease 2019 (COVID-19) has posed a serious threat to public health. There is an urgent need for discovery methods for the prevention and treatment of COVID-19 infection. Understanding immunogenicity together with immune responses are expected to provide further information about this virus. We hope that this narrative review article may create new insights for researchers to take great strides toward designing vaccines and novel therapies in the near future. The functional properties of the immune system in COVID-19 infection is not exactly clarified yet. This is compounded by the many gaps in our understanding of the SARS-CoV-2 immunogenicity properties. Possible immune responses according to current literature are discussed as the first line of defense and acquired immunity. Here, we focus on proposed modern preventive immunotherapy methods in COVID-19 infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Reviews Topics: Vaccines Limits: Humans Language: English Journal: Immunol Invest Journal subject: Allergy and Immunology Year: 2022 Document Type: Article Affiliation country: 08820139.2020.1825480

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Reviews Topics: Vaccines Limits: Humans Language: English Journal: Immunol Invest Journal subject: Allergy and Immunology Year: 2022 Document Type: Article Affiliation country: 08820139.2020.1825480