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A severe coronavirus disease 2019 patient with high-risk predisposing factors died from massive gastrointestinal bleeding: a case report.
Chen, Taojiang; Yang, Qin; Duan, Hongyu.
  • Chen T; Department of Critical Care Medicine, Chengdu Fifth People's Hospital, Chengdu, Sichuan, China.
  • Yang Q; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Duan H; Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China. 495429978@qq.com.
BMC Gastroenterol ; 20(1): 318, 2020 Sep 29.
Article in English | MEDLINE | ID: covidwho-800931
ABSTRACT

BACKGROUND:

SARS-CoV-2 is highly infectious and has been a significant public health threat. Despite typical manifestations of illness are dominated by respiratory symptom, some patients have concurrent gastrointestinal manifestations, including nausea, diarrhea, and vomiting. Massive gastrointestinal bleeding, however, has rarely been reported. CASE PRESENTATION We herein described a case of severe SARS-CoV-2 infected patient with several risk factors for poor prognosis, including male, hypertension, old age, mixed bacterial infection and multilobular infiltration on radiological imaging. After improvement of respiratory status, the onset of gastrointestinal bleeding occurred, probably resulting from direct viral invasion as evidenced by the positive findings for SARS-CoV-2 in the repeat stool specimens. Although aggressive resuscitation was administered, hematochezia was uncontrolled. The patient rapidly deteriorated, suffered from cardiac arrest, and expired.

CONCLUSIONS:

Digestive symptoms could be severe in SARS-CoV-2 infected patients, especially for the high-risk individuals with predisposing conditions. A more thorough protocol for preventing cross-infection through faecal-oral transmission should be implemented in the process of patient care and infection control.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Gastrointestinal Hemorrhage Type of study: Case report / Diagnostic study / Etiology study / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans / Male Language: English Journal: BMC Gastroenterol Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: S12876-020-01458-x

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus / Gastrointestinal Hemorrhage Type of study: Case report / Diagnostic study / Etiology study / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Humans / Male Language: English Journal: BMC Gastroenterol Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: S12876-020-01458-x