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Facile biosensors for rapid detection of COVID-19.
Xu, Lizhou; Li, Danyang; Ramadan, Sami; Li, Yanbin; Klein, Norbert.
  • Xu L; Department of Materials, Imperial College London, London, SW7 2AZ, UK. Electronic address: l.xu@imperial.ac.uk.
  • Li D; School of Cancer and Pharmaceutical Sciences, King's College London, 150 Stamford Street, London, SE1 9NH, UK.
  • Ramadan S; Department of Materials, Imperial College London, London, SW7 2AZ, UK.
  • Li Y; Department of Biological and Agricultural Engineering, University of Arkansas, Fayetteville, AR, 72701, USA.
  • Klein N; Department of Materials, Imperial College London, London, SW7 2AZ, UK.
Biosens Bioelectron ; 170: 112673, 2020 Dec 15.
Article in English | MEDLINE | ID: covidwho-807919
ABSTRACT
Currently the world is being challenged by a public health emergency caused by the coronavirus pandemic (COVID-19). Extensive efforts in testing for coronavirus infection, combined with isolating infected cases and quarantining those in contact, have proven successful in bringing the epidemic under control. Rapid and facile screening of this disease is in high demand. This review summarises recent advances in strategies reported by international researchers and engineers concerning how to tackle COVID-19 via rapid testing, mainly through nucleic acid- and antibody- testing. The roles of biosensors as powerful analytical tools are emphasized for the detection of viral RNAs, surface antigens, whole viral particles, antibodies and other potential biomarkers in human specimen. We critically review in depth newly developed biosensing methods especially for in-field and point-of-care detection of SARS-CoV-2. Additionally, this review describes possible future strategies for virus rapid detection. It helps researchers working on novel sensor technologies to tailor their technologies in a way to address the challenge for effective detection of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Biosensing Techniques / Coronavirus Infections / Clinical Laboratory Techniques / Point-of-Care Testing / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Limits: Animals / Humans Language: English Journal: Biosens Bioelectron Journal subject: Biotechnology Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Biosensing Techniques / Coronavirus Infections / Clinical Laboratory Techniques / Point-of-Care Testing / Betacoronavirus Type of study: Diagnostic study / Observational study / Prognostic study Limits: Animals / Humans Language: English Journal: Biosens Bioelectron Journal subject: Biotechnology Year: 2020 Document Type: Article