Lip necrosis in a patient with paroxysmal nocturnal hemoglobinuria: Can it be triggered by COVID-19?
J Cosmet Dermatol
; 19(12): 3168-3170, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-808315
ABSTRACT
BACKGROUND:
COVID-19 due to SARS-CoV-2 was first described in the city of Wuhan in China and spread around the world turning into a pandemic. COVID-19 can affect different organ systems, including the oral mucosa.AIMS:
Although cutaneous involvement has been defined in association with COVID-19, the number of case reports about mucosal involvement by SARS-CoV-2 is limited. Hereby, we report a case of hemorrhagic necrosis on the lip in a patient with paroxysmal nocturnal hemoglobinuria (PNH) and COVID-19 infection and briefly discuss its possible mechanism. PATIENTS The clinical features and causes of hemorrhagic necrosis on the lip in a woman are presented.RESULTS:
In our patient, we think that PNH-associated dermal micro-occlusions caused extensive painful necrosis of the lip. Additionally, COVID-19-induced endothelial damage helped to develop exaggerated hemorrhagic necrosis.CONCLUSION:
This current case presentation will contribute to the literature as another case with COVID-19 triggering mucosal involvement.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Hemoglobinuria, Paroxysmal
/
Lip
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
J Cosmet Dermatol
Journal subject:
Dermatology
Year:
2020
Document Type:
Article
Affiliation country:
Jocd.13746
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