Your browser doesn't support javascript.
Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions.
Zheng, Yue; Larragoite, Erin T; Lama, Juan; Cisneros, Isabel; Delgado, Julio C; Slev, Patricia; Rychert, Jenna; Innis, Emily A; Williams, Elizabeth S C P; Coiras, Mayte; Rondina, Matthew T; Spivak, Adam M; Planelles, Vicente.
  • Zheng Y; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Larragoite ET; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Lama J; RetroVirox, Inc., San Diego, CA.
  • Cisneros I; RetroVirox, Inc., San Diego, CA.
  • Delgado JC; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Slev P; Associated Regional and University Pathologists (ARUP) Laboratories, Salt Lake City, UT.
  • Rychert J; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Innis EA; Associated Regional and University Pathologists (ARUP) Laboratories, Salt Lake City, UT.
  • Williams ESCP; Associated Regional and University Pathologists (ARUP) Laboratories, Salt Lake City, UT.
  • Coiras M; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Rondina MT; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT.
  • Spivak AM; AIDS Immunopathology Unit, National Center of Microbiology (CNM), Instituto de Salud Carlos III, Madrid, Spain.
  • Planelles V; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT.
bioRxiv ; 2020 Sep 21.
Article in English | MEDLINE | ID: covidwho-808493
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See preprint
ABSTRACT
Antibody neutralization is an important prognostic factor in many viral diseases. To easily and rapidly measure titers of neutralizing antibodies in serum or plasma, we developed pseudovirion particles composed of the spike glycoprotein of SARS-CoV-2 incorporated onto murine leukemia virus capsids and a modified minimal MLV genome encoding firefly luciferase. These pseudovirions provide a practical means of assessing immune responses under laboratory conditions consistent with biocontainment level 2.
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Year: 2020 Document Type: Article

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Year: 2020 Document Type: Article