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Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations.
Kim, Jihoon; Neumann, Larissa; Paul, Paulina; Aratow, Michael; Bell, Douglas S; Doctor, Jason N; Hinske, Ludwig C; Jiang, Xiaoqian; Kim, Katherine K; Matheny, Michael E; Meeker, Daniella; Pletcher, Mark J; Schilling, Lisa M; SooHoo, Spencer; Xu, Hua; Zheng, Kai; Ohno-Machado, Lucila.
  • Kim J; UC San Diego Health Department of Biomedical Informatics, University of California San Diego, La Jolla, CA 92093, USA.
  • Neumann L; UC San Diego Health Department of Biomedical Informatics, University of California San Diego, La Jolla, CA 92093, USA.
  • Paul P; Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Ludwig Maximilian University of Munich, Munich, Bavaria 81377, Germany.
  • Aratow M; LMU Klinikum, Department of Anaesthesiology, Ludwig Maximilian University of Munich, Munich, Bavaria 81377, Germany.
  • Bell DS; UC San Diego Health Department of Biomedical Informatics, University of California San Diego, La Jolla, CA 92093, USA.
  • Doctor JN; San Mateo Medical Center, San Mateo, CA 94403, USA.
  • Hinske LC; Biomedical Informatics Program, UCLA Clinical and Translational Science Institute (CTSI) Los Angeles, CA 90024, USA.
  • Jiang X; USC Schaeffer Center for Health Policy and Economics, Price School of Policy, University of Southern California, Los Angeles, CA 90031, USA.
  • Kim KK; Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Ludwig Maximilian University of Munich, Munich, Bavaria 81377, Germany.
  • Matheny ME; LMU Klinikum, Department of Anaesthesiology, Ludwig Maximilian University of Munich, Munich, Bavaria 81377, Germany.
  • Meeker D; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Pletcher MJ; Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA 95817, USA.
  • Schilling LM; School of Medicine, Department of Public Health Sciences, Health Informatics Division, University of California Davis, Sacramento, CA 95817, USA.
  • SooHoo S; GRECC Tennessee Valley Healthcare System, Nashville, TN 37212, USA.
  • Xu H; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Zheng K; USC Schaeffer Center for Health Policy and Economics, Price School of Policy, University of Southern California, Los Angeles, CA 90031, USA.
  • Ohno-Machado L; Department of Preventive Medicine, Keck School of Medicine, Los Angeles, CA, USA.
medRxiv ; 2020 Sep 23.
Article in English | MEDLINE | ID: covidwho-808753
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
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ABSTRACT
There is an urgent need to answer questions related to COVID-19's clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protecting strategy, we launched a public Questions & Answers web portal (https//covid19questions.org) with analyses of comorbidities, medications and laboratory tests using data from 202 hospitals (59,074 COVID-19 patients) in the USA and Germany. We find, for example, that 8.6% of hospitalizations in which the patient was not admitted to the ICU resulted in the patient returning to the hospital within seven days from discharge and that, when adjusted for age, mortality for hospitalized patients was not significantly different by gender or ethnicity.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Year: 2020 Document Type: Article Affiliation country: 2020.09.21.20196220

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Year: 2020 Document Type: Article Affiliation country: 2020.09.21.20196220