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Provision of COVID-19 Convalescent Plasma in a Resource-Constrained State.
Ipe, Tina S; Le, Tuan; Quinn, Brian; Kellar, Stan; Clark, Melisa; Carlisle, Suzanna; Rassmann, Anja; Hennigan, Steve; Ridenour, Terry; Roberts, Anthony; Avery, David; Ryan, Stefanie; Pearson, Shanna; Kothari, Atul; Patil, Naveen.
  • Ipe TS; Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
  • Le T; Oklahoma/Texas/and Arkansas Blood Institute, Oklahoma City, Oklahoma, USA.
  • Quinn B; Department of Pathology, Baptist Health, Little Rock, Arkansas, USA.
  • Kellar S; Department of Medicine, Baptist Health, Little Rock, Arkansas, USA.
  • Clark M; Office of Research Regulatory Affairs (ORRA), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
  • Carlisle S; Office of Research Regulatory Affairs (ORRA), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
  • Rassmann A; Clinical Trials Innovation Unit (CTIU), Translational Research Institute (TRI), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
  • Hennigan S; Washington Regional Medical Center, Fayetteville, Arkansas, USA.
  • Ridenour T; Oklahoma/Texas/and Arkansas Blood Institute, Oklahoma City, Oklahoma, USA.
  • Roberts A; Community Blood Center of the Ozarks, Springfield, Missouri, USA.
  • Avery D; Clinical Trials Innovation Unit (CTIU), Translational Research Institute (TRI), University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
  • Ryan S; Arkansas Department of Health, Little Rock, Arkansas, USA.
  • Pearson S; Arkansas Department of Health, Little Rock, Arkansas, USA.
  • Kothari A; Arkansas Department of Health, Little Rock, Arkansas, USA.
  • Patil N; Arkansas Department of Health, Little Rock, Arkansas, USA.
Transfusion ; 60(12): 2828-2833, 2020 12.
Article in English | MEDLINE | ID: covidwho-808782
ABSTRACT

BACKGROUND:

Arkansas is a rural state of 3 million people. It is ranked fifth for poverty nationally. The first case of coronavirus disease 2019 (COVID-19) in Arkansas occurred on 11 March 2020. Since then, approximately 8% of all Arkansans have tested positive. Given the resource limitations of Arkansas, COVID-19 convalescent plasma (CCP) was explored as a potentially lifesaving, therapeutic option. Therefore, the Arkansas Initiative for Convalescent Plasma was developed to ensure that every Arkansan has access to this therapy. STUDY DESIGN AND

METHOD:

This brief report describes the statewide collaborative response from hospitals, blood collectors, and the Arkansas Department of Health (ADH) to ensure that CCP was available in a resource-limited state.

RESULTS:

Early contact tracing by ADH identified individuals who had come into contact with "patient zero" in early March. Within the first week, 32 patients tested positive for COVID-19. The first set of CCP collections occurred on 9 April 2020. Donors had to be triaged carefully in the initial period, as many had recently resolved their symptoms. From our first collections, with appropriate resource and inventory management, we collected sufficient CCP to provide the requested number of units for every patient treated with CCP in Arkansas.

CONCLUSIONS:

The Arkansas Initiative, a statewide effort to ensure CCP for every patient in a resource-limited state, required careful coordination among key players. Collaboration and resource management was crucial to meet the demand of CCP products and potentially save lives.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Resource Allocation / Pandemics / SARS-CoV-2 / COVID-19 / Health Resources / Health Services Accessibility Type of study: Observational study Limits: Humans Country/Region as subject: North America Language: English Journal: Transfusion Year: 2020 Document Type: Article Affiliation country: Trf.16118

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Resource Allocation / Pandemics / SARS-CoV-2 / COVID-19 / Health Resources / Health Services Accessibility Type of study: Observational study Limits: Humans Country/Region as subject: North America Language: English Journal: Transfusion Year: 2020 Document Type: Article Affiliation country: Trf.16118