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Dysimmunity and inflammatory storm: Watch out for bone lesions in COVID-19 infection.
Tao, Huaqiang; Ge, Gaoran; Li, Wenming; Liang, Xiaolong; Wang, Hongzhi; Li, Ning; Sun, Houyi; Zhang, Wei; Geng, Dechun.
  • Tao H; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Ge G; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Li W; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Liang X; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Wang H; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Li N; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Sun H; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Zhang W; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China.
  • Geng D; Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou 215000, China. Electronic address: szgengdc@suda.edu.cn.
Med Hypotheses ; 145: 110332, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-816834
ABSTRACT
At the end of 2019, a new kind of pneumonia which was proven to be supported by novel coronaviruses named SARS-CoV-2 emerges and it seems to be more complicate in its clinical course and management. Related researches have demonstrated that SARS-CoV-2 serves roles in respiratory, intestinal and neuronal diseases. Given the growing cases of COVID-19, analyzing the relevance between COVID-19 and fragile patients who suffer from bone destruction is entirely indispensable. Accordingly, the recapitulatory commentary is necessary to advance our knowledge on COVID-19 and orthopedics. In this article, we particularly clarify the possible relationship between the newly COVID-19 infection and bone lesions from the standpoints of dysimmunity and inflammatory storm.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bone Diseases / Cytokines / COVID-19 / Inflammation / Hypoxia Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article Affiliation country: J.mehy.2020.110332

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bone Diseases / Cytokines / COVID-19 / Inflammation / Hypoxia Type of study: Prognostic study Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article Affiliation country: J.mehy.2020.110332