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Engineering a Model to Study Viral Infections: Bioprinting, Microfluidics, and Organoids to Defeat Coronavirus Disease 2019 (COVID-19).
Shpichka, Anastasia; Bikmulina, Polina; Peshkova, Maria; Kosheleva, Nastasia; Zurina, Irina; Zahmatkesh, Ensieh; Khoshdel-Rad, Niloofar; Lipina, Marina; Golubeva, Elena; Butnaru, Denis; Svistunov, Andrei; Vosough, Massoud; Timashev, Peter.
  • Shpichka A; Department of Advanced Biomaterials, Institute for Regenerative Medicine, Sechenov University, Moscow, Russia.
  • Bikmulina P; Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia.
  • Peshkova M; Department of Advanced Biomaterials, Institute for Regenerative Medicine, Sechenov University, Moscow, Russia.
  • Kosheleva N; Department of Advanced Biomaterials, Institute for Regenerative Medicine, Sechenov University, Moscow, Russia.
  • Zurina I; Department of Molecular and Cell Pathophysiology, FSBSI Institute of General Pathology and Pathophysiology, Moscow, Russia.
  • Zahmatkesh E; Department of Embryology, Lomonosov Moscow State University, Faculty of Biology, Moscow, Russia.
  • Khoshdel-Rad N; Department of Advanced Biomaterials, Institute for Regenerative Medicine, Sechenov University, Moscow, Russia.
  • Lipina M; Department of Molecular and Cell Pathophysiology, FSBSI Institute of General Pathology and Pathophysiology, Moscow, Russia.
  • Golubeva E; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Butnaru D; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Svistunov A; Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Vosough M; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Timashev P; Department of Traumatology, Orthopedics and Disaster Surgery, Sechenov University, Moscow, Russia.
Int J Bioprint ; 6(4): 302, 2020.
Article in English | MEDLINE | ID: covidwho-831409
ABSTRACT
While the number of studies related to severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) is constantly growing, it is essential to provide a framework of modeling viral infections. Therefore, this review aims to describe the background presented by earlier used models for viral studies and an approach to design an "ideal" tissue model for SARS-CoV-2 infection. Due to the previous successful achievements in antiviral research and tissue engineering, combining the emerging techniques such as bioprinting, microfluidics, and organoid formation are considered to be one of the best approaches to form in vitro tissue models. The fabrication of an integrated multi-tissue bioprinted platform tailored for SARS-CoV-2 infection can be a great breakthrough that can help defeat coronavirus disease in 2019.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Int J Bioprint Year: 2020 Document Type: Article Affiliation country: IJB.V6I4.302

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Int J Bioprint Year: 2020 Document Type: Article Affiliation country: IJB.V6I4.302