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Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020).
Bai, Chunxue; Chotirmall, Sanjay H; Rello, Jordi; Alba, George A; Ginns, Leo C; Krishnan, Jerry A; Rogers, Robert; Bendstrup, Elisabeth; Burgel, Pierre-Regis; Chalmers, James D; Chua, Abigail; Crothers, Kristina A; Duggal, Abhijit; Kim, Yeon Wook; Laffey, John G; Luna, Carlos M; Niederman, Michael S; Raghu, Ganesh; Ramirez, Julio A; Riera, Jordi; Roca, Oriol; Tamae-Kakazu, Maximiliano; Torres, Antoni; Watkins, Richard R; Barrecheguren, Miriam; Belliato, Mirko; Chami, Hassan A; Chen, Rongchang; Cortes-Puentes, Gustavo A; Delacruz, Charles; Hayes, Margaret M; Heunks, Leo M A; Holets, Steven R; Hough, Catherine L; Jagpal, Sugeet; Jeon, Kyeongman; Johkoh, Takeshi; Lee, May M; Liebler, Janice; McElvaney, Gerry N; Moskowitz, Ari; Oeckler, Richard A; Ojanguren, Iñigo; O'Regan, Anthony; Pletz, Mathias W; Rhee, Chin Kook; Schultz, Marcus J; Storti, Enrico; Strange, Charlie; Thomson, Carey C.
  • Bai C; Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China.
  • Chotirmall SH; Shanghai Respiratory Research Institution, Shanghai, China.
  • Rello J; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Alba GA; Vall d'Hebron Research Institute, Barcelona, Spain.
  • Ginns LC; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
  • Krishnan JA; CHU Nîmes, Nîmes, France.
  • Rogers R; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Bendstrup E; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Burgel PR; Dept of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
  • Chalmers JD; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Chua A; Center for Rare Lung Diseases, Dept of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.
  • Crothers KA; Dept of Respiratory Medicine, Cochin Hospital, Assistance Publique Hopîtaux de Paris, Université de Paris and Institut Cochin, Inserm U1016, Paris, France.
  • Duggal A; Scottish Centre for Respiratory Research, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
  • Kim YW; Division of Pulmonary, Critical Care and Sleep Medicine, Dept of Internal Medicine, Stony Brook University, Stony Brook, NY, USA.
  • Laffey JG; Dept of Medicine, Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle WA, USA.
  • Luna CM; Dept of Critical Care, Cleveland Clinic, Cleveland OH, USA.
  • Niederman MS; Division of Pulmonary and Critical Care Medicine, Dept of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
  • Raghu G; Dept of Anesthesia and Intensive Care Medicine, Galway University Hospitals, National University of Ireland, Galway, Ireland.
  • Ramirez JA; Dept of Medicine, Pulmonary Diseases Division, Hospital de Clínicas, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Riera J; Division of Pulmonary and Critical Care, Dept of Medicine, Weill Cornell Medicine, New York NY, USA.
  • Roca O; Dept of Medicine, University of Washington, Seattle WA, USA.
  • Tamae-Kakazu M; Division of Infectious Diseases, Dept of Medicine, University of Louisville, Louisville KY, USA.
  • Torres A; Vall d'Hebron Research Institute, Barcelona, Spain.
  • Watkins RR; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
  • Barrecheguren M; Critical Care Dept, Vall d'Hebron University Hospital Barcelona, Barcelona, Spain.
  • Belliato M; Dept de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.
  • Chami HA; Vall d'Hebron Research Institute, Barcelona, Spain.
  • Chen R; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
  • Cortes-Puentes GA; Critical Care Dept, Vall d'Hebron University Hospital Barcelona, Barcelona, Spain.
  • Delacruz C; Dept de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.
  • Hayes MM; Division of Pulmonary, Critical Care, and Sleep Medicine, Spectrum Health-Michigan State University, Grand Rapids MI, USA.
  • Heunks LMA; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
  • Holets SR; Pulmonology Dept, University of Barcelona Hospital Clinic of Barcelona, IDIBAPS, Barcelona, Spain.
  • Hough CL; Dept of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
  • Jagpal S; Division of Infectious Diseases, Cleveland Clinic Akron General, Akron, OH, USA.
  • Jeon K; Respiratory Dept, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Johkoh T; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (Ciberes), Madrid, Spain.
  • Lee MM; UOC Anestesia e Rianimazione 1, IRCCS Policlinico San Matteo, Pavia, Italy.
  • Liebler J; Dept of Medicine, American University of Beirut, Beirut, Lebanon.
  • McElvaney GN; Dept of Pulmonary and Critical Care Medicine, Shenzhen Institute of Respiratory Disease, Shenzhen People's Hospital, First Affiliated Hospital of South University of Science and Technology of China, Shenzhen, China.
  • Moskowitz A; Dept of Pulmonary Medicine, Mayo Clinic, Rochester MN, USA.
  • Oeckler RA; Dept of Medicine, Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven CT, USA.
  • Ojanguren I; Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston MA, USA.
  • O'Regan A; Dept of Intensive Care, Amsterdam University Medical Center, Amsterdam, The Netherlands.
  • Pletz MW; Dept of Pulmonary Medicine, Mayo Clinic, Rochester MN, USA.
  • Rhee CK; Division of Pulmonary and Critical Care, Dept of Medicine, Oregon Health Sciences University, Portland, OR, USA.
  • Schultz MJ; Dept of Medicine, Robert Wood Johnson University Hospital, New Brunswick NJ, USA.
  • Storti E; Division of Pulmonary and Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Strange C; Dept of Radiology, Kansai Rosai Hospital, Amagaski, Japan.
  • Thomson CC; Division of Pulmonary, Critical Care and Sleep Medicine, Dept of Internal Medicine, University of Southern California, Los Angeles CA, USA.
Eur Respir Rev ; 29(157)2020 Sep 30.
Article in English | MEDLINE | ID: covidwho-835811
Semantic information from SemMedBD (by NLM)
1. 2019 novel coronavirus CAUSES Disease
Subject
2019 novel coronavirus
Predicate
CAUSES
Object
Disease
2. Acute Pneumonia PROCESS_OF Patients
Subject
Acute Pneumonia
Predicate
PROCESS_OF
Object
Patients
3. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
4. Venous Thromboembolism PROCESS_OF Patients
Subject
Venous Thromboembolism
Predicate
PROCESS_OF
Object
Patients
5. COVID-19 PROCESS_OF Survivors
Subject
COVID-19
Predicate
PROCESS_OF
Object
Survivors
6. Pharmacotherapy TREATS COVID-19
Subject
Pharmacotherapy
Predicate
TREATS
Object
COVID-19
7. Pharmacotherapy TREATS Patients
Subject
Pharmacotherapy
Predicate
TREATS
Object
Patients
8. 2019 novel coronavirus CAUSES Disease
Subject
2019 novel coronavirus
Predicate
CAUSES
Object
Disease
9. Acute Pneumonia PROCESS_OF Patients
Subject
Acute Pneumonia
Predicate
PROCESS_OF
Object
Patients
10. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
11. Venous Thromboembolism PROCESS_OF Patients
Subject
Venous Thromboembolism
Predicate
PROCESS_OF
Object
Patients
12. COVID-19 PROCESS_OF Survivors
Subject
COVID-19
Predicate
PROCESS_OF
Object
Survivors
13. Pharmacotherapy TREATS COVID-19
Subject
Pharmacotherapy
Predicate
TREATS
Object
COVID-19
14. Pharmacotherapy TREATS Patients
Subject
Pharmacotherapy
Predicate
TREATS
Object
Patients
ABSTRACT

BACKGROUND:

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.

METHODS:

An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion.

RESULTS:

The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder.

CONCLUSIONS:

The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Societies, Medical / Pulmonary Medicine / Coronavirus Infections / Advisory Committees / Consensus / Betacoronavirus / International Cooperation Type of study: Controlled clinical trial / Clinical Practice Guide / Randomized controlled trials Limits: Humans Country/Region as subject: North America / Europa Language: English Year: 2020 Document Type: Article Affiliation country: 16000617.0287-2020

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Societies, Medical / Pulmonary Medicine / Coronavirus Infections / Advisory Committees / Consensus / Betacoronavirus / International Cooperation Type of study: Controlled clinical trial / Clinical Practice Guide / Randomized controlled trials Limits: Humans Country/Region as subject: North America / Europa Language: English Year: 2020 Document Type: Article Affiliation country: 16000617.0287-2020