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Mining the Antibody Repertoire for Solutions to SARS-CoV-2.
Meng, Wenzhao; Rosenfeld, Aaron M; Luning Prak, Eline T.
  • Meng W; Perelman School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Rosenfeld AM; Perelman School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Luning Prak ET; Perelman School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Immunology University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: luning@pennmedicine.upenn.edu.
Cell Host Microbe ; 28(4): 499-501, 2020 10 07.
Article in English | MEDLINE | ID: covidwho-838112
ABSTRACT
In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Severe Acute Respiratory Syndrome / Pandemics Topics: Vaccines Limits: Humans Language: English Journal: Cell Host Microbe Journal subject: Microbiology Year: 2020 Document Type: Article Affiliation country: J.chom.2020.09.010

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Severe Acute Respiratory Syndrome / Pandemics Topics: Vaccines Limits: Humans Language: English Journal: Cell Host Microbe Journal subject: Microbiology Year: 2020 Document Type: Article Affiliation country: J.chom.2020.09.010