Can COVID-19 Mortality be Predicted in the Emergency Room?
J Coll Physicians Surg Pak
; 30(9): 928-932, 2020 Sep.
Article
in English
| MEDLINE | ID: covidwho-841654
ABSTRACT
OBJECTIVE:
To investigate the association âof white blood cell (WBC) counts, neutrophil, platelets, lymphocyte counts, C-reactive protein (CRP), neutrophil / lymphocyte ratio (NLR), derived NLR ratio (d-NLR), and platelet / lymphocyte ratio (PLR) at the time of first admission for mortality caused by COVID-19. STUDYDESIGN:
Descritive, analytical study. PLACE AND DURATION OF STUDY Department of Emergency Medicine, Sakarya University Training and Research Hospital, Turkey from March 2020 to May 2020.METHODOLOGY:
One hundred and sixty-nine patients with the diagnosis of Covid-19 were retrospectively reviewed. Patients were divided into two groups as survivors and non-survivors. Inclusion criteria were age ≥18 years, RT-PCR test positivity, hospitalisation. Patients with missing data were excluded. Data regarding age, gender, WBC counts, neutrophil, platelets, and lymphocyte, CRP, NLR, d-NLR, PLR and comorbid conditions were analysed for mortality. All tests were done with a two-sided significance of 5%. For each endpoint, the absolute and relative effects and their corresponding 95% confidence interval were calculated.RESULTS:
There was a statistically significant association between neutrophil, lymphocyte, CRP, NLR, d-NLR and PLR values (p=0.005, p<0.001, p<0.001, p<0.001, p<0.001, and p<0.001, respectively) with mortality status of the patients. The cutoff values calculated by this analysis were 67.50 years for age, 5.12 K / µl for neutrophil, 1.12 K / µl for lymphocyte, 67.78 mg / dl for CRP, 3.9 for NLR, 2.55 for d-NLR, and 148.85 for PLR.CONCLUSION:
Altered neutrophil and lymphocyte counts, NLR, d-NLR, PLR, and CRP values can be used as early predictors of mortality in Covid-19 patients. Key Words Covid-19, Mortality, Emergency, NLR, d-NLR, PLR.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Emergency Service, Hospital
Type of study:
Diagnostic study
/
Experimental Studies
/
Prognostic study
/
Randomized controlled trials
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
J Coll Physicians Surg Pak
Journal subject:
Medicine
Year:
2020
Document Type:
Article
Affiliation country:
Jcpsp.2020.09.928
Similar
MEDLINE
...
LILACS
LIS