Your browser doesn't support javascript.
Baseline Demographics and Clinical Characteristics Among 3471 US Patients Hospitalized with COVID-19 and Pulmonary Involvement: A Retrospective Study.
Best, Jennie H; Mohan, Shalini V; Kong, Amanda M; Patel, Krish; Pagel, John M; Ivanov, Boris; Brawley, Otis W; Jariwala-Parikh, Krutika; Zazzali, James L; Pauk, John.
  • Best JH; Genentech, Inc., South San Francisco, CA, USA. best.jennie@gene.com.
  • Mohan SV; Genentech, Inc., South San Francisco, CA, USA.
  • Kong AM; IBM Watson Health, Cambridge, MA, USA.
  • Patel K; Swedish Cancer Institute, Seattle, WA, USA.
  • Pagel JM; Swedish Cancer Institute, Seattle, WA, USA.
  • Ivanov B; IBM Watson Health, Cambridge, MA, USA.
  • Brawley OW; Johns Hopkins Medicine, Baltimore, MD, USA.
  • Jariwala-Parikh K; IBM Watson Health, Cambridge, MA, USA.
  • Zazzali JL; Genentech, Inc., South San Francisco, CA, USA.
  • Pauk J; Swedish Medical Center, Seattle, WA, USA.
Adv Ther ; 37(12): 4981-4995, 2020 12.
Article in English | MEDLINE | ID: covidwho-843146
ABSTRACT

INTRODUCTION:

Coronavirus disease 2019 (COVID-19) can present as a range of symptoms, from mild to critical; lower pulmonary involvement, including pneumonia, is often associated with severe and critical cases. Understanding the baseline characteristics of patients hospitalized with COVID-19 illness is essential for effectively targeting clinical care and allocating resources. This study aimed to describe baseline demographics and clinical characteristics of US patients hospitalized with COVID-19 and pulmonary involvement.

METHODS:

US patients with COVID-19 and pulmonary involvement during an inpatient admission from December 1, 2019, to May 20, 2020, were identified using the IBM Explorys® electronic health records database. Baseline (up to 12 months prior to first COVID-19 hospitalization) demographics and clinical characteristics and preadmission (14 days to 1 day prior to admission) pulmonary diagnoses were assessed. Patients were stratified by sex, age, race, and geographic region.

RESULTS:

Overall, 3471 US patients hospitalized with COVID-19 and pulmonary involvement were included. The mean (SD) age was 63.5 (16.3) years; 51.2% of patients were female, 55.0% African American, 81.6% from the South, and 16.8% from the Midwest. The most common comorbidities included hypertension (27.7%), diabetes (17.3%), hyperlipidemia (16.3%), and obesity (9.7%). Cough (27.3%) and dyspnea (15.2%) were the most common preadmission pulmonary symptoms. African American patients were younger (mean [SD], 62.5 [15.4] vs. 67.8 [6.2]) with higher mean (SD) body mass index (33.66 [9.46] vs. 30.42 [7.86]) and prevalence of diabetes (19.8% vs. 16.7%) and lower prevalence of chronic obstructive pulmonary disease (5.6% vs. 8.2%) and smoking/tobacco use (28.1% vs. 37.2%) than White patients.

CONCLUSIONS:

Among US patients primarily from the South and Midwest hospitalized with COVID-19 and pulmonary involvement, the most common comorbidities were hypertension, diabetes, hyperlipidemia, and obesity. Differences observed between African American and White patients should be considered in the context of the complex factors underlying racial disparities in COVID-19.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Black or African American / Coronavirus Infections / White People / Pandemics / Noncommunicable Diseases / Lung Diseases Type of study: Diagnostic study / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: North America Language: English Journal: Adv Ther Journal subject: Therapeutics Year: 2020 Document Type: Article Affiliation country: S12325-020-01510-y

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Black or African American / Coronavirus Infections / White People / Pandemics / Noncommunicable Diseases / Lung Diseases Type of study: Diagnostic study / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: North America Language: English Journal: Adv Ther Journal subject: Therapeutics Year: 2020 Document Type: Article Affiliation country: S12325-020-01510-y