Your browser doesn't support javascript.
COVID-19 pneumonia in lung transplant recipients: Report of 2 cases.
Cozzi, Emanuele; Faccioli, Eleonora; Marinello, Serena; Loy, Monica; Congedi, Sabrina; Calabrese, Fiorella; Romagnoli, Micaela; Cattelan, Anna M; Rea, Federico.
  • Cozzi E; Department of Cardio-Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
  • Faccioli E; Transplant Immunology Unit, Padova University-Hospital, Padova, Italy.
  • Marinello S; National Transplant Center, Rome, Italy.
  • Loy M; Thoracic Surgery and Lung Transplant Center, Department of Cardio-Thoracic, Vascular Sciences and Public Health, Padova University-Hospital, Padova, Italy.
  • Congedi S; Division of Infectious and Tropical Disease, Padova University-Hospital, Padova, Italy.
  • Calabrese F; Thoracic Surgery and Lung Transplant Center, Department of Cardio-Thoracic, Vascular Sciences and Public Health, Padova University-Hospital, Padova, Italy.
  • Romagnoli M; Department of Women's and Children's Health, University of Padova, Padova, Italy.
  • Cattelan AM; Pathological Anatomy Unit, Department of Cardio-Thoracic, Vascular Sciences and Public Health, Padova University-Hospital, Padova, Italy.
  • Rea F; Pulmonology Unit, AULSS2 Marca Trevigiana, Ospedale Cà Foncello, Treviso, Italy.
Am J Transplant ; 20(10): 2933-2937, 2020 10.
Article in English | MEDLINE | ID: covidwho-843550
ABSTRACT
Coronavirus disease 2019 (COVID-19) has been declared pandemic since March 2020. In Europe, Italy was the first nation affected by this infection. We report anamnestic data, clinical features, and therapeutic management of 2 lung transplant recipients with confirmed COVID-19 pneumonia. Both patients were in good clinical condition before the infection and were receiving immunosuppression with calcineurin inhibitors (CNI), mycophenolate mofetil, and corticosteroids. Whereas mycophenolate mofetil was withdrawn in both cases, CNI were suspended only in the second patient. The first patient always maintained excellent oxygen saturation throughout hospitalization with no need for additional oxygen therapy. He was discharged with a satisfactory pulmonary function and a complete resolution of radiological and clinical findings. However, at discharge SARS-CoV-2 RNA could still be detected in the nasopharyngeal swab and in the stools. The second patient required mechanical ventilation, had a progressive deterioration of his clinical conditions, and had a fatal outcome. Further insight into SARS-CoV-2 infection is eagerly awaited to improve the outcome of transplant recipients affected by COVID-19 pneumonia.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Lung Transplantation / Coronavirus Infections / Transplant Recipients / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Limits: Aged / Humans / Male / Middle aged Language: English Journal: Am J Transplant Journal subject: Transplantation Year: 2020 Document Type: Article Affiliation country: Ajt.15993

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Lung Transplantation / Coronavirus Infections / Transplant Recipients / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Limits: Aged / Humans / Male / Middle aged Language: English Journal: Am J Transplant Journal subject: Transplantation Year: 2020 Document Type: Article Affiliation country: Ajt.15993