Trisomy 21 and Coronavirus Disease 2019 in Pediatric Patients.

Newman, Alexander M; Jhaveri, Ravi; Patel, Ami B; Tan, Tina Q; Toia, Jacqueline M; Arshad, Mehreen

Newman, Alexander M; Jhaveri, Ravi; Patel, Ami B; Tan, Tina Q; Toia, Jacqueline M; Arshad, Mehreen.

Newman AM; Ann and Robert H. Lurie Children's Hospital, Chicago, IL. Electronic address: anewman@luriechildrens.org.
Jhaveri R; Ann and Robert H. Lurie Children's Hospital, Chicago, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL.
Patel AB; Ann and Robert H. Lurie Children's Hospital, Chicago, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL.
Tan TQ; Ann and Robert H. Lurie Children's Hospital, Chicago, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL.
Toia JM; Ann and Robert H. Lurie Children's Hospital, Chicago, IL.
Arshad M; Ann and Robert H. Lurie Children's Hospital, Chicago, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL.

J Pediatr ; 228: 294-296, 2021 01.

Article in English | MEDLINE | ID: covidwho-845393

ABSTRACT

ABSTRACT

We present 4 pediatric patients with trisomy 21 (T21) and associated comorbidities who developed coronavirus disease 2019 requiring hospitalization. A review of the literature revealed that comorbidities associated with T21 may predispose patients to severe disease. Children with T21 should be considered high risk and monitored carefully if infected with severe acute respiratory syndrome coronavirus 2.

Subject(s)

COVID-19/complications; COVID-19/epidemiology; Comorbidity; Disease Susceptibility; Down Syndrome/complications; Down Syndrome/epidemiology; Adolescent; Hospitalization; Humans; Infant; Male; Risk Factors; SARS-CoV-2

Keywords

COVID-19; Down syndrome; trisomy 21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Comorbidity / Down Syndrome / Disease Susceptibility / COVID-19 Type of study: Case report / Observational study / Prognostic study Topics: Long Covid Limits: Adolescent / Humans / Infant / Male Language: English Journal: J Pediatr Year: 2021 Document Type: Article

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