The Possible Dual Role of the ACE2 Receptor in Asthma and Coronavirus (SARS-CoV2) Infection.

Branco, Anna Cláudia Calvielli Castelo; Sato, Maria Notomi; Alberca, Ricardo Wesley

Branco, Anna Cláudia Calvielli Castelo; Sato, Maria Notomi; Alberca, Ricardo Wesley.

Branco ACCC; Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Sato MN; Laboratory of Dermatology and Immunodeficiencies, LIM-56, Department of Dermatology, School of Medicine and Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil.
Alberca RW; Laboratory of Dermatology and Immunodeficiencies, LIM-56, Department of Dermatology, School of Medicine and Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil.

Front Cell Infect Microbiol ; 10: 550571, 2020.

Article in English | MEDLINE | ID: covidwho-853923

Subject(s)

Asthma/complications; Coronavirus Infections/complications; Lung/pathology; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral/complications; Pulmonary Disease, Chronic Obstructive/complications; Angiotensin-Converting Enzyme 2; Anti-Asthmatic Agents/therapeutic use; Asthma/drug therapy; Asthma/pathology; Betacoronavirus/immunology; COVID-19; Coronavirus Infections/drug therapy; Coronavirus Infections/pathology; Cytokine Release Syndrome/blood; Cytokine Release Syndrome/pathology; Cytokines/blood; Eosinophils/immunology; Gene Expression Regulation/physiology; Humans; Lung/virology; Pandemics; Pneumonia, Viral/drug therapy; Pneumonia, Viral/pathology; Pulmonary Disease, Chronic Obstructive/pathology; SARS-CoV-2; Th2 Cells/immunology

Keywords

ACE2; COVID 19; SARS-CoV2; asthma; inflammation

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Asthma / Coronavirus Infections / Peptidyl-Dipeptidase A / Pulmonary Disease, Chronic Obstructive / Lung Topics: Long Covid Limits: Humans Language: English Journal: Front Cell Infect Microbiol Year: 2020 Document Type: Article Affiliation country: Fcimb.2020.550571

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