[COVID-19: epidemiology and clinical facts]. / COVID-19: Epidemiologische und klinische Fakten.
Radiologe
; 60(10): 893-898, 2020 Oct.
Article
in German
| MEDLINE | ID: covidwho-856126
ABSTRACT
Until July 31, 2020, about 17.6 million SARS-CoV2 infections and 680,000 deaths from COVID-19 were reported. SARS-CoV2 is most likely transmitted by droplets and probably by aerosols. Patients become infectious 2-3 days before the onset of symptoms, and persons with asymptomatic infections are also infectious. COVID-19 affects the upper respiratory tract, lungs (pneumonia, acute respiratory distress syndrome [ARDS]), heart, liver, gastrointestinal tract, and other organs. SARS-CoV2 uses ACE2 a receptor to enter host cells. Vasculitis, endothelial damage, thromboembolic events and organ failure are accompanied by a massive cytokine response. Elderly people and those with pre-existing diseases are particularly vulnerable. An efficient antiviral therapy is not yet available. Severely ill patients may benefit from dexamethasone and early treatment of complications. Candidate vaccines are currently being tested in clinical studies.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Pandemics
/
Betacoronavirus
Type of study:
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Humans
Language:
German
Journal:
Radiologe
Year:
2020
Document Type:
Article
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