The risk of respiratory tract infections in patients with psoriasis treated with interleukin 23 pathway-inhibiting biologics: A meta-estimate of pivotal trials relevant to decision making during the COVID-19 pandemic.

Syed, Maha N; Shin, Daniel B; Wan, Marilyn T; Winthrop, Kevin L; Gelfand, Joel M

Syed, Maha N; Shin, Daniel B; Wan, Marilyn T; Winthrop, Kevin L; Gelfand, Joel M.

Syed MN; Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Shin DB; Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Wan MT; Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Winthrop KL; Division of Infectious diseases and Public Health, Oregon Health and Sciences University, Portland, Oregon.
Gelfand JM; Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: Joel.Gelfand@pennme

J Am Acad Dermatol ; 83(5): 1523-1526, 2020 11.

Article in English | MEDLINE | ID: covidwho-866785

Subject(s)

Biological Products/adverse effects; Coronavirus Infections/immunology; Interleukin-23 Subunit p19/antagonists & inhibitors; Pneumonia, Viral/immunology; Psoriasis/drug therapy; Respiratory Tract Infections/epidemiology; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/adverse effects; Antibodies, Monoclonal, Humanized/administration & dosage; Antibodies, Monoclonal, Humanized/adverse effects; Betacoronavirus/immunology; Biological Products/administration & dosage; COVID-19; Clinical Decision-Making; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Coronavirus Infections/epidemiology; Coronavirus Infections/prevention & control; Coronavirus Infections/transmission; Humans; Interleukin-23 Subunit p19/metabolism; Odds Ratio; Pandemics/prevention & control; Pneumonia, Viral/epidemiology; Pneumonia, Viral/prevention & control; Pneumonia, Viral/transmission; Psoriasis/immunology; Respiratory Tract Infections/chemically induced; Respiratory Tract Infections/immunology; Respiratory Tract Infections/prevention & control; Risk Assessment; SARS-CoV-2; Signal Transduction/drug effects; Signal Transduction/immunology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Psoriasis / Respiratory Tract Infections / Biological Products / Coronavirus Infections / Interleukin-23 Subunit p19 Type of study: Observational study / Prognostic study / Randomized controlled trials / Reviews Limits: Humans Language: English Journal: J Am Acad Dermatol Year: 2020 Document Type: Article

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