Waning Antibody Responses in Asymptomatic and Symptomatic SARS-CoV-2 Infection.

Choe, Pyoeng Gyun; Kang, Chang Kyung; Suh, Hyeon Jeong; Jung, Jongtak; Song, Kyoung-Ho; Bang, Ji Hwan; Kim, Eu Suk; Kim, Hong Bin; Park, Sang Won; Kim, Nam Joong; Park, Wan Beom; Oh, Myoung-Don

Choe, Pyoeng Gyun; Kang, Chang Kyung; Suh, Hyeon Jeong; Jung, Jongtak; Song, Kyoung-Ho; Bang, Ji Hwan; Kim, Eu Suk; Kim, Hong Bin; Park, Sang Won; Kim, Nam Joong; Park, Wan Beom; Oh, Myoung-Don.

Emerg Infect Dis ; 27(1)2021 01.

Article in English | MEDLINE | ID: covidwho-868883

ABSTRACT

ABSTRACT

We investigated the kinetics of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in 7 asymptomatic persons and 11 patients with pneumonia. The geometric mean titer of neutralizing antibodies declined from 219.4 at 2 months to 143.7 at 5 months after infection, indicating a waning antibody response.

Subject(s)

Antibodies, Neutralizing/blood; Antibodies, Viral/blood; Antibody Formation; COVID-19/immunology; SARS-CoV-2/immunology; Humans

Keywords

2019 novel coronavirus disease; COVID-19; ELISA; SARS-CoV-2; antibodies; coronavirus; coronavirus disease; neutralizing antibodies; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; waning immunity; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antibodies, Neutralizing / SARS-CoV-2 / COVID-19 / Antibodies, Viral / Antibody Formation Limits: Humans Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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