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Clinical management of COVID-19: Experiences of the COVID-19 epidemic from Groote Schuur Hospital, Cape Town, South Africa.
Mendelson, M; Boloko, L; Boutall, A; Cairncross, L; Calligaro, G; Coccia, C; Dave, J A; De Villiers, M; Dlamini, S; Frankenfeld, P; Gina, P; Gule, M V; Hoare, J; Hofmeyr, R; Hsiao, M; Joubert, I; Kahn, T; Krause, R; Kroopman, A; Levin, D; Maughan, D; Mazondwa, S; Meintjes, G; Nordien, R; Ntusi, N; Papavarnavas, N; Peter, J; Pickard, H; Raubenheimer, P; Said-Hartley, Q; Singh, P; Wasserman, S; Schuur Hospital Covid-Response Team, On Behalf Of The Groote.
  • Mendelson M; Division of Infectious Diseases and HIV Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa. marc.mendelson@uct.ac.za.
S Afr Med J ; 110(10): 973-981, 2020 08 26.
Article in English | MEDLINE | ID: covidwho-869268
ABSTRACT
The SARS-CoV-2 pandemic has presented clinicians with an enormous challenge in managing a respiratory virus that is not only capable of causing severe pneumonia and acute respiratory distress syndrome, but also multisystem disease. The extraordinary pace of clinical research, and particularly the surge in adaptive trials of new and repurposed treatments, have provided rapid answers to questions of whether such treatments work, and has resulted in corticosteroids taking centre stage in the management of hospitalised patients requiring oxygen support. Some treatment modalities, such as the role of anticoagulation to prevent and treat potential thromboembolic complications, remain controversial, as does the use of high-level oxygen support, outside of an intensive care unit setting. In this paper, we describe the clinical management of COVID-19 patients admitted to Groote Schuur Hospital, a major tertiary level hospital at the epicentre of South Africa's SARS-CoV-2 epidemic during its first 4 months.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Tertiary Care Centers / Hospitals, University Type of study: Diagnostic study / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Humans Country/Region as subject: Africa Language: English Journal: S Afr Med J Year: 2020 Document Type: Article Affiliation country: SAMJ.2020.v110i10.15157

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Tertiary Care Centers / Hospitals, University Type of study: Diagnostic study / Observational study / Prognostic study / Qualitative research Topics: Long Covid Limits: Humans Country/Region as subject: Africa Language: English Journal: S Afr Med J Year: 2020 Document Type: Article Affiliation country: SAMJ.2020.v110i10.15157