Defusing SARS-CoV-2: Emergency Brakes in a Vaccine Failure Scenario.
ACS Pharmacol Transl Sci
; 3(6): 1425-1426, 2020 Dec 11.
Article
in English
| MEDLINE | ID: covidwho-872660
ABSTRACT
Deactivation of primed SARS-CoV-2 prior to cell entry constitutes an emergency brake in COVID-19 infection if vaccine-induced antibodies fail to block recognition of the human angiotensin-converting enzyme 2 (hACE2) receptor. The timing and locus for the therapeutic intervention are dictated by the cell entry mechanism and by the selective advantage of the dominant D614G mutation.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Topics:
Vaccines
Language:
English
Journal:
ACS Pharmacol Transl Sci
Year:
2020
Document Type:
Article
Affiliation country:
Acsptsci.0c00152
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