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Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness.
Pierron, Denis; Pereda-Loth, Veronica; Mantel, Marylou; Moranges, Maëlle; Bignon, Emmanuelle; Alva, Omar; Kabous, Julie; Heiske, Margit; Pacalon, Jody; David, Renaud; Dinnella, Caterina; Spinelli, Sara; Monteleone, Erminio; Farruggia, Michael C; Cooper, Keiland W; Sell, Elizabeth A; Thomas-Danguin, Thierry; Bakke, Alyssa J; Parma, Valentina; Hayes, John E; Letellier, Thierry; Ferdenzi, Camille; Golebiowski, Jérôme; Bensafi, Moustafa.
  • Pierron D; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France. denis.pierron@univ-tlse3.fr.
  • Pereda-Loth V; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France.
  • Mantel M; Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1, Bron, France.
  • Moranges M; Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1, Bron, France.
  • Bignon E; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR7272, Nice, France.
  • Alva O; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France.
  • Kabous J; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France.
  • Heiske M; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France.
  • Pacalon J; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR7272, Nice, France.
  • David R; Université Côte d'Azur, CHU de Nice, Nice Memory Clinic, Nice, France.
  • Dinnella C; University of Florence, Florence, Italy.
  • Spinelli S; University of Florence, Florence, Italy.
  • Monteleone E; University of Florence, Florence, Italy.
  • Farruggia MC; Interdepartmental Neuroscience Program, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Cooper KW; Department of Neurobiology and Behavior, University of California, Irvine, CA, 92697, USA.
  • Sell EA; Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.
  • Thomas-Danguin T; Centre des Sciences du Goût et de l'Alimentation, INRAE, CNRS, AgroSup-Dijon, University Bourgogne Franche-Comté, Dijon, France.
  • Bakke AJ; The Pennsylvania State University, Philadelphia, PA, 19104, USA.
  • Parma V; Temple University, Philadelphia, PA, 19122, USA.
  • Hayes JE; The Pennsylvania State University, Philadelphia, PA, 19104, USA.
  • Letellier T; Équipe de Médecine Evolutive Faculté de chirurgie dentaire; UMR5288; CNRS/Université Paul-Sabiater Toulouse III, Toulouse, 31400, France.
  • Ferdenzi C; Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, University Claude Bernard Lyon 1, Bron, France.
  • Golebiowski J; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR7272, Nice, France. jerome.golebiowski@univ-cotedazur.fr.
  • Bensafi M; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 711-873, South Korea. jerome.golebiowski@univ-cotedazur.fr.
Nat Commun ; 11(1): 5152, 2020 10 14.
Article in English | MEDLINE | ID: covidwho-872697
ABSTRACT
In response to the COVID-19 pandemic, many governments have taken drastic measures to avoid an overflow of intensive care units. Accurate metrics of disease spread are critical for the reopening strategies. Here, we show that self-reports of smell/taste changes are more closely associated with hospital overload and are earlier markers of the spread of infection of SARS-CoV-2 than current governmental indicators. We also report a decrease in self-reports of new onset smell/taste changes as early as 5 days after lockdown enforcement. Cross-country comparisons demonstrate that countries that adopted the most stringent lockdown measures had faster declines in new reports of smell/taste changes following lockdown than a country that adopted less stringent lockdown measures. We propose that an increase in the incidence of sudden smell and taste change in the general population may be used as an indicator of COVID-19 spread in the population.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Taste Disorders / Communicable Disease Control / Coronavirus Infections / Pandemics / Olfaction Disorders Type of study: Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: Europa Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2020 Document Type: Article Affiliation country: S41467-020-18963-y

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Taste Disorders / Communicable Disease Control / Coronavirus Infections / Pandemics / Olfaction Disorders Type of study: Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Country/Region as subject: Europa Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2020 Document Type: Article Affiliation country: S41467-020-18963-y