Possible affective cognitive cerebellar syndrome in a young patient with COVID-19 CNS vasculopathy and stroke.
BMJ Case Rep
; 13(10)2020 Oct 15.
Article
in English
| MEDLINE | ID: covidwho-873485
ABSTRACT
Early case series suggest that about one-third of patients with COVID-19 present with neurological manifestations, including cerebrovascular disease, reported in 2%-6% of hospitalised patients. These are generally older patients with severe infection and comorbidities. Here we discuss the case of a previously fit and well 39-year-old man who presented with fever and respiratory symptoms, evolving in pneumonia with hypoxia but only requiring continuous positive airway pressure. After resolution of the respiratory disease, the patient developed focal neurology and was found to have bilateral occipital, thalamic and cerebellar infarcts. A diagnosis of COVID-19 central nervous system vasculopathy was made. He developed a florid neuropsychiatric syndrome, including paranoia, irritability, aggression and disinhibition, requiring treatment with antipsychotics and transfer to neurorehabilitation. Neuropsychometry revealed a wide range of cognitive deficits. The rapid evolution of the illness was matched by fast resolution of the neuropsychiatric picture with mild residual cognitive impairment.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Behavioral Symptoms
/
Brain Stem
/
Cerebellar Diseases
/
Cerebellum
/
Coronavirus Infections
/
Brain Infarction
/
Pandemics
/
Cognitive Dysfunction
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
/
Qualitative research
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Bcr-2020-237926
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