Platelet aggregates, a marker of severe COVID-19 disease.
J Clin Pathol
; 74(11): 750-751, 2021 Nov.
Article
in English
| MEDLINE | ID: covidwho-873566
ABSTRACT
Thrombocytopenia is common in an intensive care unit (ICU) setting due to endogenous and iatrogenic factors. Despite that, thrombocytopenia in patients with severe COVID-19 infections is surprisingly uncommon. By examining the blood film of 20 ICU patients with COVID-19, we observed the presence of platelet aggregates and macrothrombocytes indicating increased platelet activity. We compared these findings with 20 blood films of non-severe COVID-19 cases where these findings were absent. These morphology features could be consistent with severe COVID-19 infection and is further evidence of the important role that platelets play when COVID-19 manifests with thrombotic complications or respiratory failure.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Thrombosis
/
Blood Platelets
/
COVID-19
Topics:
Long Covid
Limits:
Aged
/
Humans
/
Middle aged
Language:
English
Journal:
J Clin Pathol
Year:
2021
Document Type:
Article
Affiliation country:
Jclinpath-2020-206933
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