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Multiple Biological Roles of Extracellular Vesicles in Lung Injury and Inflammation Microenvironment.
Su, Gang; Ma, Xiaohong; Wei, Haidong.
  • Su G; Institute of Genetics, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
  • Ma X; Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
  • Wei H; Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Biomed Res Int ; 2020: 5608382, 2020.
Article in English | MEDLINE | ID: covidwho-886830
ABSTRACT
Lung injury and inflammation are complex pathological processes. The influence and crosstalk between various cells form a characteristic microenvironment. Extracellular vesicles from different cell sources in the microenvironment carry multiple cargo molecules, which affect the pathological process through different pathways. Here, we mainly discussed the mechanism of crosstalk between alveolar epithelial cells and different immune cells through extracellular vesicles in lung inflammation and reviewed the mechanism of extracellular vesicles released by blood and airways on lung inflammation. Finally, the role of extracellular vesicles in viral infection of the lung was also described.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Injury / Cellular Microenvironment / Extracellular Vesicles / Inflammation Topics: Long Covid Limits: Animals / Humans Language: English Journal: Biomed Res Int Year: 2020 Document Type: Article Affiliation country: 2020

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Injury / Cellular Microenvironment / Extracellular Vesicles / Inflammation Topics: Long Covid Limits: Animals / Humans Language: English Journal: Biomed Res Int Year: 2020 Document Type: Article Affiliation country: 2020