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Zinc and COVID-19: Basis of Current Clinical Trials.
Pal, Amit; Squitti, Rosanna; Picozza, Mario; Pawar, Anil; Rongioletti, Mauro; Dutta, Atanu Kumar; Sahoo, Sibasish; Goswami, Kalyan; Sharma, Praveen; Prasad, Rajendra.
  • Pal A; Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Kalyani, West Bengal, 741245, India. maximus1134@gmail.com.
  • Squitti R; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Picozza M; Neuroimmunology Unit, IRCSS Fondazione Santa Lucia, 00143, Rome, Italy.
  • Pawar A; Department of Zoology, DAV University, Jalandhar, Punjab, India.
  • Rongioletti M; Department of Laboratory Medicine, Research and Development Division, San Giovanni Calibita Fatebenefratelli Hospital, Isola Tiberina, Rome, Italy.
  • Dutta AK; Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Kalyani, West Bengal, 741245, India.
  • Sahoo S; Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Kalyani, West Bengal, 741245, India.
  • Goswami K; Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Kalyani, West Bengal, 741245, India.
  • Sharma P; Department of Biochemistry, AIIMS, Jodhpur, Rajasthan, India.
  • Prasad R; Department of Biochemistry, MM Institute of Medical Sciences and Research, Mullana, Ambala 133207, Haryana, India.
Biol Trace Elem Res ; 199(8): 2882-2892, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-888280
ABSTRACT
Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients, societies, and economic and healthcare systems around the world. Like many other diseases, the host immune system determines the progress of COVID-19 and fatality. Modulation of inflammatory response and cytokine production using immunonutrition is a novel concept that has been applied to other diseases as well. Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in immunity, is currently being used in some clinical trials against COVID-19. This review integrates the contemporary studies of role of zinc in antiviral immunity along with discussing its potential role against COVID-19, and ongoing COVID-19 clinical trials using zinc.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zinc / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Biol Trace Elem Res Year: 2021 Document Type: Article Affiliation country: S12011-020-02437-9

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zinc / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Biol Trace Elem Res Year: 2021 Document Type: Article Affiliation country: S12011-020-02437-9