Prognosis of COVID-19 in patients with vein thrombosis: a systematic review and meta-analysis.
Eur Rev Med Pharmacol Sci
; 24(19): 10279-10285, 2020 10.
Article
in English
| MEDLINE | ID: covidwho-890963
ABSTRACT
OBJECTIVE:
SARS-CoV-2 is currently affecting millions of humans worldwide, thus contributing to the COVID-19 pandemic. Thromboembolic events have a higher incidence among patients with COVID-19, but there are few reports on the relationship between the prognosis of COVID-19 patients and thromboembolic events. The objectives of this meta-analysis were to explore the relationship between the prognosis of COVID-19 patients and thromboembolic events. MATERIALS ANDMETHODS:
Medline (PubMed), the Web of Science, Embase, and the Cochrane Library were searched for case-control studies that included data on vein thrombosis in patients with COVID-19 and were published in English, between January 1 and July 25, 2020. According to the inclusion and exclusion criteria, the included data were confirmed, the prognoses of patients with and without concurrent thromboembolic events were compared, and the odds ratio (OR) was used as the effect size.RESULTS:
Eighteen studies (2,030 patients) were included. Thromboembolic events complicated a total of 609 COVID-19 patients. The combined OR of the mortality of COVID-19 patients with thromboembolic events was 1.93 (95% CI 1.13-3.27), that of ICU treatment rate was 2.63 (95% CI 1.49-4.67), and that of treatment with invasive mechanical ventilation was 3.14 (95% CI 1.97-5.02).CONCLUSIONS:
As compared with COVID-19 patients with and without thromboembolism, the mortality, ICU treatment rate, and invasive mechanical ventilation treatment rate of COVID-19 patients with thromboembolism were found to be increased significantly, and the prognosis was worse.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Venous Thrombosis
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Eur Rev Med Pharmacol Sci
Journal subject:
Pharmacology
/
Toxicology
Year:
2020
Document Type:
Article
Affiliation country:
Eurrev_202010_23252
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