Marine Natural Products as a Source of Drug Leads against Respiratory Viruses: Structural and Bioactive Diversity.
Curr Med Chem
; 28(18): 3568-3594, 2021.
Article
in English
| MEDLINE | ID: covidwho-892410
ABSTRACT
Respiratory viruses, including influenza virus, respiratory syncytial virus, coronavirus, etc., have seriously threatened the human health. For example, the outbreak of severe acute respiratory syndrome coronavirus, SARS, affected a large number of countries around the world. Marine organisms, which could produce secondary metabolites with novel structures and abundant biological activities, are an important source for seeking effective drugs against respiratory viruses. This report reviews marine natural products with activities against respiratory viruses, the emphasis of which was put on structures and antiviral activities of these natural products. This review has described 167 marinederived secondary metabolites with activities against respiratory viruses published from 1981 to 2019. Altogether 102 references are cited in this review article.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Orthomyxoviridae
/
Biological Products
/
Pharmaceutical Preparations
Limits:
Humans
Language:
English
Journal:
Curr Med Chem
Journal subject:
Chemistry
Year:
2021
Document Type:
Article
Affiliation country:
0929867327666201026150105
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