Evaluation of two point of care technologies for measuring monoclonal antibody therapeutic-A concentrations in blood.
Bioanalysis
; 12(20): 1449-1458, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-892489
ABSTRACT
Aim:
Current blood monitoring methods require sample collection and testing at a central lab, which can take days. Point of care (POC) devices with quick turnaround time can provide an alternative with faster results, allowing for real-time data leading to better treatment decisions for patients. Results/Methodology:
An assay to measure monoclonal antibody therapeutic-A was developed on two POC devices. Data generated using 75 serum samples (65 clinical & ten spiked samples) show correlative results to the data generated using Gyrolab technology.Conclusion:
This case study uses a monoclonal antibody therapeutic-A concentration assay as an example to demonstrate the potential of POC technologies as a viable alternative to central lab testing with quick results allowing for real-time decision-making.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Point-of-Care Systems
/
Antibodies, Monoclonal
Type of study:
Experimental Studies
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Bioanalysis
Year:
2020
Document Type:
Article
Affiliation country:
Bio-2020-0193
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