Biosafety Level 2 cabinet UV-C light exposure of sports antidoping human urine samples does not affect the stability of selected prohibited substances.
Drug Test Anal
; 13(2): 460-465, 2021 Feb.
Article
in English
| MEDLINE | ID: covidwho-893219
ABSTRACT
The current study examined the stability of several antidoping prohibited substances analytes in urine after 15-min exposure to UV-C light in a Biosafety Level 2 cabinet. The urine matrices were exposed within the original antidoping bottles with the aim to destroy DNA/RNA and possible SARS CoV-2. The analytes small molecules Phase I and Phase II metabolites and peptides, in total 444, endogenous, internal standards, and prohibited substances, pH, and specific gravity in urine were studied. The accredited analytical methods were used by Anti-Doping Laboratory Qatar for the comparison of data of the same urine samples analyzed with and without UV-C exposure. In the study conditions, no problems of stability were detected in the substances spiked in the urine samples exposed in the UV-C irradiation.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Substance Abuse Detection
/
Urinalysis
/
Anabolic Agents
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Drug Test Anal
Journal subject:
Pharmacology
Year:
2021
Document Type:
Article
Affiliation country:
Dta.2954
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